Transcription factor E3 is a protein that in humans is encoded by the TFE3 gene. [5][6][7] TFE3, a member of the helix-loop-helix family of transcription factors, binds to the mu-E3 motif of the …

2024年12月25日 · TFE3 (Transcription Factor Binding To IGHM Enhancer 3) is a Protein Coding gene. Diseases associated with TFE3 include Intellectual Developmental Disorder, X-Linked, …

2023年3月11日 · TFE3 participates in the metabolism of energy in the body by regulating pathways such as glucose and lipid metabolism, mitochondrial metabolism, and autophagy. …

In this work, we gather the available data regarding the key clinical and pathological features of these TFE3-rearranged renal epithelial and mesenchymal neoplasms. We seek to propose a …

Transcription factor binding to IGHM enhancer 3 (TFE3) is a gene that encodes a protein that promotes the expression of genes downstream of transforming growth factor beta signaling.

2025年2月6日 · Here we report that TFE3 fusions transcriptionally rewire tRCCs toward oxidative phosphorylation (OXPHOS), contrasting with the highly glycolytic nature of most other renal …

2021年9月6日 · TFE3 -translocation renal cell carcinoma (TFE3 -tRCC) is a rare and heterogeneous subtype of kidney cancer with no standard treatment for advanced disease. …

The TFE3 gene encodes a transcription factor involved in the regulation of many proteins implicated in carcinogenesis, including TGF, Met, Rb, Folliculin, Ets, and E-cadherin. It is …

6 天之前 · Boosting TFE3 levels reversed autophagy defects observed in dopamine-producing neurons as a consequence of alpha-synuclein accumulation. This increase in TFE3 also …

2025年3月6日 · TFE3 rearranged renal cell carcinoma (TFE3 rRCC) is a unique subtype of renal cell carcinoma characterized by high expression of TFE3 fusion proteins. The wild-type TFE3 …