2024年12月25日 · RBP1 (Retinol Binding Protein 1) is a Protein Coding gene. Diseases associated with RBP1 include Blepharophimosis and Endometrial Hyperplasia. Among its related pathways are Visual phototransduction and Diseases associated with visual transduction. Gene Ontology (GO) annotations related to this gene include transporter activity and retinal binding.

RBP1 is the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision.

视黄醇结合蛋白 1 (RBP1)负责调节组织中维甲酸的稳态，有报道称RBP1在包括OSCC在内的几种人类癌症中异常表达，然而，RBP1在OSCC发病中的作用和分子机制尚不清楚。

视黄醇结合蛋白 (Retinol-Binding Protein,RBP)是血液中维生素的转运蛋白，由肝脏合成、广泛分布于血液、脑脊液、尿液及其他体液中。 测定视黄醇结合蛋白能早期发现肾小管的功能损害，并能灵敏反映肾近曲小管的损害程度，可作为肾功能早期损害和监护治疗的指标，还可作为肝功能早期损害和监护治疗的指标。

2025年2月8日 · Gene target information for RBP1 - retinol binding protein 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Cellular retinol binding protein 1 transfection reduces proliferation and AKT-related gene expression in H460 non-small lung cancer cells. The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.

Biased expression in ovary (RPKM 127.5), adrenal (RPKM 41.0) and 6 other tissues. 该基因编码参与将视黄醇 (维生素 A 醇) 从肝脏储存部位转运至外周组织的载体蛋白。 维生素 A 是一种脂溶性维生素，是生长、繁殖、上皮组织分化和视力所必需的。 已发现该基因编码不同异构体的多个转录变体。 [RefSeq 提供，2008 年 8 月]

The retinoblastoma binding protein 1 (RBP1) appears to be an important factor in the repression of E2F-dependent transcription by the retinoblastoma protein (pRB) family. The recent identification of the breast carcinoma associated antigen (BCAA) as an RBP1-like protein led us to investigate its bio …

2012年10月3日 · RBP1 promoter hypermethylation is found in nearly all IDH1 and IDH2 mutant gliomas and is associated with improved patient survival. Because RBP1 is involved in retinoic acid synthesis, our results suggest that dysregulation of retinoic acid metabolism may contribute to glioma formation along the ID …

2020年6月25日 · Retinol-binding protein 1 (RBP1) is involved in several physiological functions, including the regulation of the metabolism and retinol transport. Studies have shown that it plays an important role in the pathogenesis of several types of cancer. However, the role of RBP1 and its correlation with aut …