2023年9月27日 · Often shows lymphocytosis with a spectrum of lymphocytes, plasmacytoid lymphocytes and plasma cells Rouleaux formation of red blood cells is routinely seen Cold agglutinin or cryoglobulin may be present Bone marrow (Arch Pathol Lab Med 2013;137:580) Involvement in almost all cases Aspirate is the most helpful sample in morphologic diagnosis

1 天前 · Lymphocytes range from small to intermediate and large in size Plasma cells, plasmacytoid cells and histiocytes are variably present, less frequently accompanied by eosinophils Sinuses are regularly occupied by immunoblasts, monocytoid B cells and histiocytes Immunoblasts can be binucleated, mimicking HRS

2013年11月1日 · Found in hilar region between the sinuses, composed mostly of small B and T lymphocytes, plasmacytoid lymphocytes, plasmablasts and plasma cells. Sinuses: Carry lymph from afferent to efferent lymphatics Subcapsular sinus is below capsule and partially lined by endothelium Becomes "medullary" as it approaches the hilum and is lined by macrophages

Small lymphocytes, plasmacytoid cells and plasma cells Small lymphocytes, monocytoid cells and plasma cells Large cells with round eccentric nucleus and prominent nucleoli Phenotype: Cytoplasmic light chain restriction; CD38+, CD138+, MUM1+, CD19-, CD56 variable, CD20-, PAX5-, cyclin D1-, MYC-, no p53 overexpression

2021年8月9日 · Salivary gland FNA diagnostic of a benign neoplasm (pleomorphic adenoma 60 - 70%, Warthin tumor 20 - 30%, other tumors 10%)

3 天之前 · Papulonodular lesion show dermal, intraepithelial neoplastic lymphocytes Positive staining - normal B cells, NK cells, naive / resting T cells (those not exposed to antigens), medullary thymocytes and plasmacytoid dendritic cells ( Am J Pathol 2001;159:237 )

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) (Am J Surg Pathol 2019;43:1429) Mature plasmacytoid dendritic cell proliferations (Curr Hematol Malig Rep 2018;13:477) Systemic mastocytosis (Leukemia 2016;30:914) Hairy cell leukemia (Am J Clin Pathol 2011;136:625)

2020年1月13日 · Persistent (more than 6 months) increase in the number of peripheral blood large granular lymphocytes, usually 2-20 x 10⁹ Distinct T cell population with coexpression of one or more NK cell associated antigens (CD16, CD56 or CD57) and decreased CD2, CD5 or CD7 expression Proof of T cell clonality by a molecular or flow cytometry study

2022年7月27日 · Atypical lymphocytes CD10, BCL6 and BCL2 positive Clonal B cell population BCL2::IGH translocation Mantle cell lymphoma: Mantle zone pattern may mimic HVCD Atypical lymphocytes, CD5 and cyclin D1 or SOX11 positive Clonal B cell population CCND1::IGH translocation Reactive lymph node enlargement: Lack characteristic histological features of CD

2023年4月27日 · Histologic features include architectural destruction and a mixed infiltrate of cells, including B cells at different stages of maturation such as immunoblasts, small lymphoid cells, plasmacytoid cells, plasma cells (Am J Clin Pathol 2017;147:129, Blood 2011;117:4726) Intermixed T cells and histiocytes are commonly seen