2024年12月25日 · PDGFRA (Platelet Derived Growth Factor Receptor Alpha) is a Protein Coding gene. Diseases associated with PDGFRA include Gist-Plus Syndrome and Gastrointestinal …

The PDGFRA gene provides instructions for making a protein called platelet-derived growth factor receptor alpha (PDGFRA), which is part of a family of proteins called receptor tyrosine kinases …

Platelet-derived growth factor receptor A (PDGFRA) mutations occur in approximately 10–15% of gastrointestinal stromal tumors (GISTs). These tumors with PDGFRA mutations have a …

PDGFRA/Pdgfra gene is regulated by at least seven first exons in human and mouse. our findings support a pathogenetic relationship between telocyte hyperplasia and both inflammatory …

Platelet-derived growth factors (PDGF) bind to two closely related receptor tyrosine kinases, PDGF receptor α and β, which are encoded by the PDGFRA and PDGFRB genes.

2023年12月2日 · Our high-resolution imaging, transcriptional profiling, and organoid assays identify regional subpopulations and supportive capacities of purified mouse corpus and antral …

2025年2月25日 · Pdgfra regulates multipotent cell differentiation towards chondrocytes via inhibiting Wnt9a/beta-catenin pathway during chondrocranial cartilage development. Dynamic …

PDGFRA Fusion Genes. Chronic myeloid leukemia (CML; 608232) is characterized by the presence of the BCR (151410)/ABL (189980) fusion gene, usually in association with a …

2025年2月8日 · Clinical resource with information about PDGFRA, A genome-wide association study for corneal curvature identifies the platelet-derived growth factor receptor α …

2025年3月13日 · PDGFRA is crucial to tumorigenesis and frequently genomically altered in high-grade glioma (HGG). In a comprehensive dataset of pediatric HGG (n = 261), we detect …