2024年12月25日 · OPN5 (Opsin 5) is a Protein Coding gene. Diseases associated with OPN5 include Cycloplegia. Among its related pathways are GPCR downstream signalling and Class …

2020年9月2日 · Opsin 5 (also known as neuropsin or OPN5) is a highly conserved opsin that is sensitive to visible violet light 1, 2. In mice, OPN5 is a known photoreceptor in the retina 3 and …

2019年10月21日 · Organotypic cultures of murine outer ear and vibrissal skin entrain to a light-dark cycle ex vivo, requiring cis-retinal chromophore and Opn5 gene function. Short …

2022年4月1日 · Here we present the human Neuropsin (hOPN5) for specific and repetitive manipulation of G q signaling in vitro and in vivo with high spatio-temporal resolution. …

The current study clearly determines the absorption maxima of mammalian OPN5 and is the first to report a UV photoreceptor protein in human beings. We also present several lines of …

2019年4月1日 · Here, we show that opsin 5 (OPN5; also known as neuropsin)-dependent retinal light responses regulate vascular development in the postnatal eye. In Opn5 -null mice, …

Objectives: To investigate the function and potential mechanism of opsin 5 (OPN5), a photoreceptor responsive to UVR wavelengths, in melanogenesis in HEMs. Methods: Melanin …

2011年10月17日 · Here we report that mammalian neuropsin (OPN5) encoded by the Opn5 gene is a UV-sensitive photoreceptor.

OPN5 was capable of activating heterotrimeric G protein Gi in a UV-dependent manner. Immuno-blotting analyses of mouse tissue extracts identified the retina, the brain and, unexpectedly, …

2003年11月20日 · We report the isolation of a novel mammalian opsin-like gene, Opn5, the first member of a new opsin family. We have determined its gene structure, chromosomal …