Nusinersen - Wikipedia
Nusinersen, [7] marketed as Spinraza, [4] is a medication used in treating spinal muscular atrophy (SMA), a rare neuromuscular disorder. [8] [4] In December 2016, it became the first approved drug used in treating this disorder.
Nusinersen (Spinraza®) – Spinal Muscular Atrophy (SMA)
Nusinersen, marketed in the U.S. as Spinraza ® (Biogen) is the first therapy approved for the treatment of SMA. SMA results from mutations in a gene known as SMN1, which encodes a protein (Survival Motor Neuron, or SMN) important for motor neuron survival.
Nusinersen injection Uses, Side Effects & Warnings - Drugs.com
2024年9月12日 · Nusinersen works by helping the body produce a protein essential to the function of nerves that control muscle movement. This protein is lacking in people with an inherited disorder called spinal muscular atrophy caused by a mutation in a specific gene.
Official Patient Site | SPINRAZA® (nusinersen)
SPINRAZA ® (nusinersen) is a prescription medicine used to treat spinal muscular atrophy (SMA) in pediatric and adult patients. Increased risk of bleeding complications has been observed after administration of similar medicines.
Nusinersen (Spinraza) for Spinal Muscular Atrophy Treatment
One of the latest breakthroughs in care for patients with spinal muscular atrophy is the FDA approval of a new medicine called nusinersen (brand name Spinraza) for the treatment of SMA in children and adults.
Spinraza: Uses, Dosage, Side Effects, Warnings - Drugs.com
2023年4月4日 · Spinraza (nusinersen) is a type of medication called an antisense oligonucleotide. It is used to treat children and adults with spinal muscular atrophy (SMA), a type of motor neuron disease.
The Antisense Oligonucleotide Nusinersen for Treatment of Spinal ...
An antisense oligonucleotide (ASO) drug, nusinersen, provides an upcoming and promising treatment option for SMA and represents a novel pharmacological approach with a mechanism of action relevant for other neurodegenerative disorders. Nusinersen begins with four initial loading doses that are followed by three maintenance doses per year.
Nusinersen Injection: MedlinePlus Drug Information
Nusinersen injection is used for the treatment of spinal muscular atrophy (an inherited condition that reduces muscle strength and movement) in infants, children, and adults. Nusinersen injection is in a class of medications called antisense oligonucleotide inhibitors.
Nusinersen: A Treatment for Spinal Muscular Atrophy - PubMed
It is a novel modified antisense oligonucleotide designed to treat SMA caused by mutations in chromosome 5q that lead to survival motor neuron protein deficiency. Nusinersen has been studied for safety, pharmacokinetics, and efficacy in …
Long-term nusinersen treatment across a wide spectrum of spinal ...
2023年8月4日 · Nusinersen is the first disease-modifying drug for all SMA types. We report on effectiveness and safety data from 120 adults and older children with SMA types 1c-3 treated with nusinersen.