2024年12月25日 · NFKBIA (NFKB Inhibitor Alpha) is a Protein Coding gene. Diseases associated with NFKBIA include Ectodermal Dysplasia And Immunodeficiency 2 and Hypohidrotic …

2020年9月21日 · Emerging studies indicate that dysregulated NF-κB activity causes inflammation-related diseases as well as cancers, and NF-κB has been long proposed as the potential …

2013年8月1日 · The NFKBIA gene provides instructions for making one piece (the alpha subunit) of the IKK protein complex, which is a group of related proteins that regulates the activity of …

Our findings represent the first characterization of NFKBIA and IκBα as maternal effectors in both the bovine oocyte and embryo. We suggest a role for NFKBIA as a marker of NF-κB/p65 …

2025年2月20日 · HIV-1 Tat upregulates the expression of nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA, IkappaB alpha) in human primary T cells …

2024年12月10日 · Phosphorylated IκBα predicts poor prognosis in activated B-cell lymphoma and its inhibition with thymoquinone induces apoptosis via ROS release. Hussain AR, Uddin S, …

Gene ID: 4792, updated on 9-Feb-2025. This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts …

The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm.

2021年1月18日 · DNA damage induces two kinetically and functionally distinct phases of NF‐κB activation. The first is anti‐apoptotic and driven by the IKK cascade, while the second …

该基因编码 NF-kappa-B 抑制剂家族的成员，该家族包含多个锚蛋白重复结构域。 编码的蛋白质与 REL 二聚体相互作用，抑制参与炎症反应的 NF-kappa-B/REL 复合物。 编码的蛋白质通过核定 …