Serine/threonine protein kinase MST4, also known as mammalian STE20-like protein kinase 4 (MST-4), is a protein that in humans is encoded by the MST4 gene. [5] The product of this …

2018年1月22日 · mst4是哺乳动物 stk丝氨酸/苏氨酸激酶家族的成员。 已知mst4激活p-erk以诱导细胞生长和转化，并促进前列腺癌、肝细胞癌的上皮-间充质转变和癌症转移的进展。同 …

2023年10月13日 · Primary immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disorder in which macrophages play a critical role. Mammalian sterile-20-like kinase 4 (MST4), …

2013年2月28日 · 该研究阐述了支架蛋白mo25对ste20家族激酶mst4的激活机制。 mst4属于ste20激酶gckiii亚家族，在细胞极性、增值、转化与迁移等过程中发挥重要作用。mo25与假激 …

2023年6月1日 · MST4, a serine/threonine-protein kinase, plays a crucial role in regulating cell migration and polarity in normal and tumor cells. MST4 modulates ERK and AKT signaling …

2015年5月13日 · 该项研究揭示了mst4在天然免疫中的重要功能与作用机制，为免疫炎症相关疾病的诊疗提供了新的思路。 相关研究成果已申请专利。 近年来，周兆才研究组围绕STRIPAK这 …

2015年2月2日 · Here we report that germinal center kinase MST4 responded dynamically to bacterial infection and acted as a negative regulator of inflammation. We found that MST4 …

We verify the effects of MST4 on irradiation-induced gastric death, and also investigate effects of MST4 activating autophagy in GC cell lines with various in vitro assays using western blotting. …

2020年11月19日 · Knockdown of MST4 activated epithelial-mesenchymal transition (EMT) process, significantly increasing the ability of invasion and migration in choriocarcinoma cell …

2022年12月15日 · The mammalian STE 20-like protein kinase 4 (MST4) gene is highly expressed in several cancer types, but little is known about the role of MST4 in breast cancer, and the …