2024年12月25日 · MKLN1 (Muskelin 1) is a Protein Coding gene. Diseases associated with MKLN1 include Aggressive Periodontitis and Acrodermatitis. Among its related pathways are Regulation of pyruvate metabolism and Respiratory electron transport.

2022年6月15日 · We show that Mkln1 deletion alters dendrite branching and spine structure, coinciding with enhanced AMPAR-mediated synaptic transmission but selective impairment in synaptic potentiation...

2024年12月25日 · MKLN1-AS (MKLN1 Antisense RNA) is an RNA Gene, and is affiliated with the lncRNA class. ... VectorBuilder Custom and pre-made pooled libraries (ie. CRISPR, shRNA, barcode) Expressed in primordial germ cell in gonad, male germ line stem cell (sensu Vertebrata) in testis, skeletal muscle tissue and 100 other cell types or tissues.

RNA specificity category based on RNA sequencing data from cancer cell lines in the Human Protein Atlas grouped according to type of cancer. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.

2022年7月17日 · mkln 和 igs 双通证，nft pass 特殊权益 在经济部分，Tatsumeeko 采用了链游中常见的双通证模式。 其中 MKLN 为治理通证，总量为 10 亿； IGS 为游戏内的功能通证，没有设置上限。

Muskelin 1 antisense RNA (MKLN1-AS) shows prognostic value in hepatitis B virus-hepatocellular carcinoma. The aim of this study is to investigate the detailed biological role of MKLN1-AS and Yes-associated transcriptional regulator 1 (YAP1)-related mechanisms.

2022年6月15日 · We show that Mkln1 deletion alters dendrite branching and spine structure, coinciding with enhanced AMPAR-mediated synaptic transmission but selective impairment in synaptic potentiation maintenance. We identify muskelin at excitatory synapses and highlight its role in regulating dendritic spine actin stability.

2024年3月12日 · Linux命令”mkln”用于创建一个软链接（symbolic link）或者硬链接（hard link）。 软链接是一个指向文件或者目录的符号链接，在创建软链接时，会创建一个新的文件，其内容是指向源文件或者目录的路径。

Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (PubMed:29911972).

2024年6月6日 · As one of the selective mechanisms within the UPS, CTLH-MKLN specifically induces HMGCS1 ubiquitination via the N-terminal-proline-containing degradation signal (Pro/N-degron), leading to its proteasome-mediated degradation. This, in turn, reduces the production of mevalonate pathway metabolites and ultimately inhibits cell proliferation.