2004年5月9日 · The basic helix-loop-helix (bHLH) gene Ascl1 (also known as Mash1) is coexpressed with Nkx2-2 in the neuroepithelial domain of the hindbrain, which gives rise to 5 …

2013年6月5日 · Ascl1/Mash1 is a proneural transcription factor previously implicated in embryonic oligodendrogenesis and operating in genetic interaction with Olig2, an essential transcriptional …

Progenitors in the telencephalic subventricular zone (SVZ) remain mitotically active throughout life, and produce different cell types at embryonic, postnatal and adult stages. Here we show …

Transcription Factor Mash1 is a key factor involved in direct lineage conversion into neurons, along with other transcription factors like Ascl1, Brn2, and Myt1L. It plays a crucial role in …

2007年4月18日 · Using Mash1 null mutant mice, we show that Mash1 is required for the generation of an early population of OPCs in the ventral forebrain between embryonic day …

Ascl1 (previously Mash1) is a bHLH transcription factor essential for neuronal differentiation and specification in the nervous system. Although it has been studied for its role in several neural …

MASH1 is a useful adjunct marker for differentiating small cell carcinoma of the lung from Merkel cell carcinoma. Merkel cell carcinoma is the cutaneous counterpart of small cell carcinoma, …

2011年3月31日 · Ascl1 (Mash1) is a bHLH transcription factor essential for neural differentiation during embryogenesis but its role in adult neurogenesis is less clear.

2025年2月8日 · MASH1 is a useful adjunct marker for differentiating small cell carcinoma of the lung from Merkel cell carcinoma. Tumor marker mASH1 was highly (sensitivity of 71%) and …

Mash1 is a basic helix-loop-helix (bHLH) transcription factor, which has an important role in Notch signaling and the differentiation of GABAergic neurons [18, 19]. The Notch signaling pathway …