Microtubule-associated protein 2 (MAP2) is the predominant cytoskeletal regulator within neuronal dendrites, abundant and specific enough to serve as a robust somatodendritic marker. It influences microtubule dynamics and microtubule/actin ...

2024年12月25日 · MAP2 (Microtubule Associated Protein 2) is a Protein Coding gene. Diseases associated with MAP2 include Central Neurocytoma and Olivopontocerebellar Atrophy. Among its related pathways are TGF-Beta Pathway and CNTF Signaling. Gene Ontology (GO) annotations related to this gene include structural molecule activity and calmodulin binding.

Microtubule-associated proteins (MAPs) are a family of proteins that influence this property. We showed previously that MAP2, a neuron-specific protein that stabilizes microtubules in the dendrites of postmitotic neurons, is induced in primary cutaneous melanoma but is absent in metastatic melanomas.

什么是 MAP2 ？ 微管相关蛋白 （Microtubule-associated protein）2 或 MAP2 是一种用作成熟神经元标记物的蛋白质。 基因 MAP2 编码这种蛋白质。 MAP2 属于 MAP2/Tau 家族。 它有四种亚型，即 MAP2a、MAP2b、MAP2c 和 MAP2d。

2025年3月4日 · HIV-1 gp120/MBL complex co-localizes with MAP2 and is transported along the microtubules in human primary neurons: PubMed: env: Ascorbate supplementation prevents the deleterious upregulation of iNOS and associated neuronal (MAP2) and astrocytic (GFAP) protein expression and structural changes caused by gp120 in human brain cell cultures ...

Microtubule Associated Protein 2 (MAP2) is a protein that is specific to neurons and plays a crucial role in maintaining the structural integrity of the cytoskeleton and regulating various neuronal functions.

Here we will review the current knowledge about the regulation of MAP2 function through phosphorylation/dephosphorylation and its relevance in the broader context of neuronal functions.

Microtubule-associated proteins (MAPs) are a family of proteins that influence this property. We showed previously that MAP2, a neuron-specific protein that stabilizes microtubules in the dendrites of postmitotic neurons, is induced in primary cutaneous melanoma but is absent in metastatic melanomas.

2022年9月16日 · Here we review the understood structure and functions of MAP2, including in neurite outgrowth, synaptic plasticity, and regulation of protein folding/transport. We also describe known and potential mechanisms by which MAP2 can …

Microtubule-associated protein 2 (MAP2) is a neuronal phosphoprotein that regulates the structure and stability of microtubules, neuronal morphogenesis, cytoskeleton dynamics, and organelle trafficking in axons and dendrites.