Myosin VIIA is an unconventional myosin with the longest tail (1360 aa). The tail is expected to dimerize, resulting in a two-headed molecule.

2024年12月25日 · MYO7A (Myosin VIIA) is a Protein Coding gene. Diseases associated with MYO7A include Usher Syndrome, Type I and Deafness, Autosomal Recessive 2. Among its …

Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that …

The MYO7A gene provides instructions for making a protein called myosin VIIA, which is part of a group of proteins called unconventional myosins. Learn about this gene and related health …

A new pathogenic compound heterozygous mutation in the MYO7A gene has been discovered, which provides more diagnostic evidence for the autosomal recessive non-syndromic …

2020年4月29日 · Mutations in myosin-VIIa (MYO7A) cause Usher syndrome type 1, characterized by combined deafness and blindness. MYO7A is proposed to function as a motor that tensions …

2022年3月9日 · myo7a具有高度的遗传异质性和基因多效性。myo7a基因突变既可导致非综合征型耳聋(dfna11和dfnb2)，也可引起同时伴有内耳和视网膜病变的综合征型耳聋

The MYO7A gene encodes a protein classified as an unconventional myosin. Unconventional myosins are motor molecules with structurally conserved heads that move along actin …

2025年1月4日 · Title: Novel compound heterozygous synonymous and missense variants in the MYO7A gene identified by next-generation sequencing in a Chinese family with nonsyndromic …

用于研究Usher综合症1型和常染色体隐性非综合征性耳聋2型。 这个基因的人类同源物涉及Leber先天性夜盲；Usher综合症（多种）；听觉系统疾病（多种）；和先天性眼球震颤。 与 …