MCM7 - Wikipedia
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication.
MCM7 Gene - GeneCards | MCM7 Protein | MCM7 Antibody
2024年12月25日 · MCM7 (Minichromosome Maintenance Complex Component 7) is a Protein Coding gene. Diseases associated with MCM7 include Anisometropia and Farsightedness. …
MCM7 promotes cancer progression through cyclin D1 …
2017年2月9日 · Mechanistically, knockdown of MCM7 significantly inhibited cellular proliferation in vitro and HCC tumorigenicity in vivo. Cyclin D1 was proved to be regulated by MCM7–MAPK …
MCM7 minichromosome maintenance complex component 7
Homozygous mutation in MCM7 causes autosomal recessive primary microcephaly and intellectual disability. MCM7 affects the cisplatin resistance of liver cancer cells and the …
Cell：我国科学家领衔解析出人类MCM2-7复合物的三维结构，有 …
2023年1月15日 · 六个MCM基因--- MCM2至MCM7（MCM2-7）---的产物形成一种六亚基的环状复合物，作为DNA解链机器---DNA复制螺旋酶---的催化核心。 在细胞中，为了启动DNA复 …
MCM基因家族 - 知乎 - 知乎专栏
2022年4月19日 · MCM基因家族包括MCM2~7六个成员，广泛存在于包括从酵母到人类等真核生物中，具有调控细胞分裂的作用。 MCM名称来源为minichromosome mantenance，即微小染色 …
The DNA Replication Licensing Factor Miniature Chromosome …
Miniature chromosome maintenance 7 (MCM7) is an essential component of DNA replication licensing complex. Recent studies indicate that MCM7 is amplified and overexpressed in a …
微染色体维护复杂组件 7（MCM7）基因 | MCE
由该基因编码的蛋白质是高度保守的微型染色体维护蛋白 (MCM) 之一，对于启动真核基因组复制至关重要。 由 MCM 蛋白形成的六聚体蛋白复合物是复制前复合物 (pre_RC) 的关键组成部 …
MCM complex members MCM3 and MCM7 are associated with a ... - Nature
2021年3月2日 · Through exome and chromium genome sequencing, supported by functional studies, we identify biallelic pathogenic variants in MCM7 and a strong candidate biallelic …
Mcm7——多功能的Mcm蛋白 - 百度学术
Mcm7是微小染色体维持蛋白家族成员之一,与其他的Mcm蛋白形成异多聚体,调节DNA的复制.它与转录成分关联,可能与RNA合成即转录有关,并且增殖细胞或组织高表达Mcm7,可以作为肿瘤生 …