
Basic biology and role of interleukin-17 in immunity and inflammation
Interleukin-17 (IL-17, also known as IL-17A) is a key cytokine that links T cell activation to neutrophil mobilization and activation. As such, IL-17 can mediate protective innate immunity …
Interleukin-17 and its target genes: mechanisms of interleukin-17 ...
Interleukin-17 (IL-17) has emerged as a central player in the mammalian immune system. Although this cytokine exerts a host-defensive role in many infectious diseases, it promotes …
The IL-17 Family of Cytokines in Health and Disease - PubMed
2019年4月16日 · Here, we discuss the functions of the IL-17 family, with a focus on the balance between the pathogenic and protective roles of IL-17 in cancer and autoimmune disease, …
Interleukin-17 and its expanding biological functions - PMC
Interleukin-17 (IL-17) and IL-17-producing cells have been shown to play important roles in inflammation and the immune response. IL-17 is believed to be mainly produced by T helper …
IL-17 Inhibitors: How They Work, What They Treat, Types
2024年3月22日 · IL-17 inhibitors block the inflammatory pathway of interleukin-17A. These biologic medications are an extremely effective FDA-approved treatment option for people with …
The IL-17 family in diseases: from bench to bedside - Nature
2023年10月11日 · Interleukin 17 (IL-17) is an important cytokine that has several roles in host defense responses against mucosal infections; additionally, it is a primary pathologic cytokine …
IL-17 and IL-17-producing cells in protection versus pathology
2022年7月5日 · IL-17A and IL-17F are produced by CD4 + and CD8 + T cells, γδ T cells, and various innate immune cell populations in response to IL-1β and IL-23, and they mediate …
Critical role of interleukin (IL)-17 in inflammatory and immune ...
2020年1月1日 · Interleukin 17 (IL-17) is a proinflammatory cytokine that has been the focus of intensive research because of its crucial role in the pathogenesis of different diseases across …
IL-17 receptor–based signaling and implications for disease
2019年11月19日 · IL-17 is a highly versatile pro-inflammatory cytokine crucial for a variety of processes, including host defense, tissue repair, the pathogenesis of inflammatory disease …
IL-17 family: cytokines, receptors and signaling - PubMed
The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial roles in host defense against microbial organisms and in the development of inflammatory diseases.
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