The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in …

The Ilyushin Il-4 (DB-3F) (Russian: Ильюшин Ил-4 (ДБ-3Ф); NATO reporting name: Bob) [1] is a Soviet twin-engined long-range bomber and torpedo bomber, widely used by the Soviet Air …

In this review, recent advances in understanding these three IL-4-related branch points—alternative splicing of IL-4, differential receptor engagement by IL-4, and differential …

2021年9月7日 · Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells, …

Interleukin-4 (IL-4) Like IL-17, IL-4 has also been reported to regulate the overall activity of neural networks. IL-4 acts presynaptically to increase inhibitory synaptic transmission.

2025年1月1日 · IL-4 secreted by immune cells reduces the levels of inflammatory factors such as IL-1β, TNF-α, IL-6, and iNOS in the joint cavity; ameliorates synovial thickening and joint …

IL-4 has been called the "prototypic immunoregulatory cytokine." Like many cytokines, it can affect a variety of target cells in multiple ways. IL-4 has an important role in regulating antibody …

IL-4 has been extensively studied in the context of its role in immunity. Accumulating evidence indicates, however, that it also plays a critical role in higher functions of the normal brain, such …

2024年12月25日 · Moreover, IL-4, a type 2 cytokine, mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation. This …

Here we describe our current understanding of the organization of the IL-4 receptor, of the signaling pathways that are induced as a result of receptor occupancy, and of the various …