Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. [4] [5] [6] IL-13 was first cloned in 1993 and is located on chromosome 5q31.1 with a length of 1.4kb. [4] It has a …

Interleukin 13 (IL-13) is a cytokine that is responsible for promoting Th2 responses in humans and is released by T cells, mast cells, and eosinophils. It is typically associated with allergic …

IL-13 is a cytokine that is produced by different T-cell subsets and dendritic cells. IL-13 shares many biologic activities with IL-4. This is due to the fact that IL-13– and IL-4–receptor …

IL-13 was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. It …

2023年1月13日 · We have identified IL-13 and its receptor IL-13Ra1 as neuronal, synaptic proteins in mouse, rat, and human brains, whose engagement upregulates the …

IL-13 down-regulates PGE2 both directly and indirectly through effects on PGES and COX-2. IL-13 also induces 15-LO that is correlated with asthma severity. IL-13 induction of 15-LO …

2. What We Know about IL-13 Comes from Studies of Its Biology in the Immune System. The cytokines Interleukin 13 (IL-13) and interleukin-4 (IL-4) are two secreted proteins recognized …

This review provides an update on the role of IL-13 in AD and discusses the different strategies aimed at interfering with its biologic activity as well as their potential in a precision medicine …

IL-13 is a critical mediator of allergic inflammation. Although it shares many functional properties with IL-4, it has been shown to have distinct functions. Furthermore, IL-13 is more important …

IL-13 is involved in the processes contributing to the transition from metabolic-dysfunction-associated steatosis to MASH. IL-13 is a Th2-specific cytokine that induces the alternative …