
Allograft inflammatory factor 1 - Wikipedia
Allograft inflammatory factor 1 (AIF-1) also known as ionized calcium-binding adapter molecule 1 (IBA1) is a protein that in humans is encoded by the AIF1 gene. [5][6] The AIF1 gene is located within a segment of the major histocompatibility complex class III region.
Iba1 (AIF1) 靶点介绍及实验小贴士 | Abcam 中文官网
Iba1靶点介绍 蛋白功能. Iba1(离子钙结合适配器分子1),也称为同种异体移植炎症因子1(AIF1),是一种进化上保守的细胞浆钙结合蛋白。 Iba1是细胞骨架结合蛋白,促进细胞膜运动与RAC激活,并在RAC信号通路及吞噬过程中发挥作用。
Iba1, F4/80, CD68, GFAP染色假阳性?如何标记胶质细胞?| 靶点解 …
Iba1是细胞骨架结合蛋白,促进细胞膜运动与RAC激活,并在RAC信号通路及吞噬作用中发挥作用。 Iba1促进血管平滑肌细胞及T淋巴细胞增殖,促进淋巴细胞迁移,在巨噬细胞激活与功能中发挥作用。
Ionized Calcium Binding Adaptor Molecule 1 (IBA1) - PubMed
2021年6月17日 · IBA1 is a novel, highly sensitive, and specific marker for diagnosing neoplasms of monocytic/histiocytic and DC origin.
小胶质细胞标记物 - Abcam中文官网
离子钙结合衔接分子 1 (Iba1) 是小胶质细胞和巨噬细胞特异性的钙结合蛋白,参与激活的小胶质细胞的细胞膜皱褶形成和吞噬作用。 经抗-Iba1 (ab5076) 抗体染色的小鼠脑组织切片。 CX3CR1是一种趋化因子受体,存在于CNS中小胶质细胞和巨噬细胞的表面,可被神经元分泌的CX3CL1(趋化因子)激活。 经抗-CX3CR1(绿色) (ab8021) 抗体染色的人小胶质细胞(由单核细胞诱导而来)。 F4/80 是一种位于巨噬细胞和静息小胶质细胞表面的糖蛋白,分子量为 160 KDa。 经抗 …
小胶质细胞标志物 | Cell Signaling Technology
iba1/aif-1 是一种进化上保守的钙结合蛋白。 作为 F-肌动蛋白结合蛋白,Iba1/AIF-1 可能会重塑小胶质细胞的肌动蛋白细胞骨架。 Iba1/AIF-1 在单核细胞谱系的细胞中独特表达,因此,靶向该蛋白的抗体被广泛用于标记大脑和其他组织中的小胶质细胞/巨噬细胞。
Microglia/macrophage-specific protein Iba1 binds to fimbrin …
Ionized calcium binding adaptor molecule 1 (Iba1) is a microglia/macrophage-specific calcium-binding protein. Iba1 has the actin-bundling activity and participates in membrane ruffling and phagocytosis in activated microglia.
胶质细胞活化的标志物 - 哔哩哔哩
离子钙结合衔接分子1(Ionized calcium binding adapter molecule 1, Iba1, )是在小胶质细胞中特异性表达的一种钙结合蛋白。Iba1 抗体目前已被广泛用作小胶质细胞的标记物。Iba1是一种细胞骨架成分,参与肌动蛋白交联并参与迁移。
Silencing the Cytoskeleton Protein Iba1 (Ionized Calcium Binding ...
Iba1 (ionized calcium binding adapter protein 1) is a cytoskeleton protein specific only for microglia and macrophages, where it acts as an actin-cross linking protein. Although frequently regarded as a marker of activation, its involvement in cell migration, membrane ruffling, phagocytosis or in mi …
IBA1 Marker: Myeloid Cell Identification and Neuroimmune Impact
4 天之前 · IBA1 is a defining marker for myeloid-lineage cells, particularly microglia and macrophages, due to its exclusive expression in these populations. Unlike markers shared across multiple immune cell types, IBA1 effectively distinguishes myeloid cells …