Intravenous Therapy for Hypertensive Emergencies, Part 1
Hydralazine. Hydralazine is a peripheral vasodilator that causes relaxation of arteriolar smooth muscle by inhibiting calcium ion release from the sarcoplasmic reticulum. ... For additional …
Drug Therapy During Labor and Delivery - Page 2 - Medscape
During labor and delivery, the most commonly used antihypertensive agents are i.v. hydralazine hydrochloride (5-10 mg every 15-20 minutes until desired response) and i.v. labetalol …
Intravenous Therapy for Hypertensive Emergencies, Part 2
Only 2 patients in the hydralazine-treated group developed hypotension, while palpitations (p = 0.01) and maternal tachycardia (p = 0.05) occurred significantly more often in patients treated …
Severe Hypertension: Would You Refer This Patient? - Medscape
2024年2月1日 · Current medications include losartan 100 mg daily, amlodipine 10 mg daily, hydralazine 50 mg three times daily, lovastatin 40 mg nightly, and aspirin 81 mg daily.
Why Use Isosorbide Dinitrate vs Isosorbide Mononitrate?
2010年8月23日 · The US Food and Drug Administration (FDA)-approved formulation for heart failure is the fixed combination of ISDN/hydralazine tablet (BiDil®). Isosorbide dinitrate is also …
Pharmacotherapeutic Options for the Treatment of Preeclampsia
The recommended dosage of hydralazine hydrochloride is 5-10 mg (i.v. or i.m.) every 15 minutes up to a maximum dose of 30 mg i.m. or 20 mg i.v. If the patient experiences no change in …
Are Nitrate-Free Intervals Really Needed? - Medscape
2013年10月11日 · Nitrate tolerance is characterized by loss of hemodynamic and antianginal effects after repeated dosing; higher and higher doses are needed to obtain the same …
Key Steps to Optimizing GDMT in Heart Failure - Medscape
2023年8月1日 · Steps three and four are to optimize therapy further if patients remain symptomatic. Hydralazine and nitrates are indicated in patients who identify as African …
Recommendations for Use of Medications With Continuous …
Hydralazine. Coadministration of hydralazine with enteral nutrition results in decreased drug absorption and decreased serum concentrations of the medication. However, hydralazine has …
Hypertension in Pregnancy: 5 Things Clinicians Should Know
2024年10月11日 · Janet Wright, MD, director of CDC's Division for Heart Disease and Stroke Prevention, shares how clinicians can better improve detection and management of …