2024年12月25日 · HOXB2 (Homeobox B2) is a Protein Coding gene. Diseases associated with HOXB2 include Pancreatic Cancer and Leukemia, Acute Myeloid. Among its related pathways …

Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene. [5][6][7] This gene is a member of the Antp homeobox family and encodes a nuclear protein with a …

2024年1月20日 · We found that the reduced expression of HOXB2 was correlated with the metastatic abilities (epithelial-to-mesenchymal transition) of TNBC cells. Further, we revealed …

2024年1月20日 · HOXB2 bound to the promoter regions of MATN3 and ECM2 and regulated their transcription levels. Forced expression of HOXB2 effectively prevented TNBC progression and …

Hoxb2, Hoxb5, Hoxb7, and Hoxc4 genes were found to regulate self-renewal and differentiation of murine MSCs . HOX genes have been shown to play critical roles during osteogenesis of …

Hoxb2 is a direct target for regulation by PLZF in the developing CNS and suggest that deregulation of Hox gene expression may contribute to APL pathogenesis. This gene is a …

2020年5月26日 · The top five HOX genes most associated with genomic instability and DNA repair pathways after the enrichment analysis were HOXC12, HOXC11, HOXC5, HOXB2, and …

2023年10月10日 · HOXB2 is a Putative Tumour Promotor in Human Bladder Cancer. Lung cancer susceptibility genetic variants modulate HOXB2 expression in the lung.

2021年8月20日 · Using a mouse model and human breast cancer cell lines, we show that estrogen suppresses HOXB2 expression. Suppression of HOXB2 by PPT, a known ERα …

它包含在位于 17 号染色体上的同源框 B 基因簇中。 编码的蛋白质作为参与发育的序列特异性转录因子发挥作用。 该基因表达增加与胰腺癌有关。 [RefSeq 提供，2008 年 7 月] This gene is a …