
Hepatocyte growth factor - Wikipedia
Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells and T cells.
Human Growth Hormone (HGH): Benefits, Risks, and Uses - WebMD
2024年5月1日 · Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases. The...
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Hepatocyte growth factor: A regulator of inflammation and …
2015年4月1日 · Hepatocyte growth factor (HGF) is a pleiotropic cytokine that has been extensively studied over several decades, but was only recently recognized as a key player in mediating protection of many types of inflammatory and autoimmune diseases.
Hepatocyte growth factor: A regulator of inflammation and ... - PubMed
Hepatocyte growth factor (HGF) is a pleiotropic cytokine that has been extensively studied over several decades, but was only recently recognized as a key player in mediating protection of many types of inflammatory and autoimmune diseases.
HGF and MET: From Brain Development to Neurological Disorders
Hepatocyte growth factor (HGF) and its tyrosine kinase receptor, encoded by the MET cellular proto-oncogene, are expressed in the nervous system from pre-natal development to adult life, where they are involved in neuronal growth and survival.
Presence of a mobilizable intracellular pool of hepatocyte …
2002年4月15日 · Hepatocyte growth factor (HGF), a heparin-binding factor, is synthesized as a single-chain inactive precursor (pro-HGF), which is converted by proteolysis to an active heterodimer (mature HGF). HGF has pleiotropic activities and has been implicated in the regulation of mitogenesis, motogenesis, and morphogenesis of epithelial and endothelial cells.
Hepatocyte Growth Factor - an overview | ScienceDirect Topics
Hepatocyte Growth Factor (HGF) is a polypeptide that promotes cell growth, motility, and morphogenesis, and acts as a cell survival factor in the liver. It is synthesized and secreted as a precursor that is processed into a biologically active form.
The discovery of Hepatocyte Growth Factor (HGF) and its …
It has been more than 25 years since HGF was discovered as a mitogen of hepatocytes. HGF is produced by stromal cells, and stimulates epithelial cell proliferation, motility, morphogenesis and angiogenesis in various organs via tyrosine phosphorylation of its receptor, c-Met.
Hepatocyte growth factor in physiology and infectious diseases
Hepatocyte growth factor (HGF) is a pleiotropic cytokine composed of an α-chain and a β-chain, and these chains contain four kringle domains and a serine protease-like structure, respectively. The receptor for HGF was identified as the c-met proto-oncogene product of transmembrane receptor tyrosine kinase.