We ranked regulatory evolution rates of human genes and molecular pathways by using high throughput data on five histone marks from the ENCODE project [30] for five human cell lines. …

2024年10月10日 · In this study, we reconstruct high-resolution 3D genome maps based on genomic regions marked by H3K9ac, an active histone modification that dynamically responds …

In the current study, we explored the roles of H3K4me3, H3K36me3, and H3K9ac modifications in the epigenomic regulation of gene expression in Paulownia during infection by the PaWB …

2018年12月17日 · We conducted an epigenome-wide association study using the histone 3 lysine 9 acetylation (H3K9ac) mark in 669 aged human prefrontal cortices; in contrast with amyloid-β, …

2024年1月30日 · Here, we profiled the genome-wide landscapes of H3K9ac for paired adjacent normal (Nor), primary ESCC (EC) and metastatic lymph node (LNC) esophageal tissues from …

2023年2月20日 · These findings highlight epigenetic reprogramming through H3K9ac and H3K14ac as a novel approach for driving neuron-fate-induction of GBM cells.

To study the mitotic regulation of H3K9ac, we used an array of inhibitors targeting specific histone deacetylases. We evaluated the involvement of the targeted enzymes in regulating H3K9ac …

H3K9 does double duty. It can turn genes on by getting acetylated, but can silence them just as easily when methylated. H3K9ac is a particularly important acetylation: it is highly correlated …

2012年8月24日 · Acetylation of specific lysine residues of histones plays a key role in regulating gene expression. Here we have investigated the genome-wide occurrence of two histone …

2010年4月21日 · Histone modifications play an important role in gene regulation. Acetylation of histone 3 lysine 9 (H3K9ac) is generally associated with transcription initiation and unfolded …