
H3K4me3 - Wikipedia
H3K4me3 is an epigenetic modification to the DNA packaging protein Histone H3 that indicates tri-methylation at the 4th lysine residue of the histone H3 protein and is often involved in the …
组蛋白修饰 | 一文带你了解H3K4me3 - 知乎 - 知乎专栏
H3K4me3是最重要的甲基化修饰之一,真核生物中该修饰在转录起始位点普遍发生,通常在基因的启动子附近富集,并且与基因的转录相关,是表观遗传学一个标志,其水平可以反映出转录的 …
H3K4me3 - 百度百科
H3K4me3,中文名组蛋白第三亚基四号赖氨酸的三甲基化,H3K4me3是指组蛋白第三亚基四号赖氨酸的三甲基化;一个特定的组蛋白赖氨酸甲基转移酶( HMT ),将三甲基团转移到组蛋白 3上。
H3K4甲基化(H3K4me3)在生物学和疾病中的作用 - 简书
2025年1月3日 · H3K4me3的广泛区域(broad domains)是指基因组中H3K4me3与比典型的两个或三个核小体更大范围的区域相关,这些区域与持续的基因表达有关。广泛的H3K4me3区域 …
组蛋白修饰 - Abcam中文官网
了解最常见的组蛋白修饰,例如 H3K4me3,H3K9me3 和 H3K27me3 以及其 readers, writers, 和 erasers。 下载完整表观遗传学应用指南
H3K4me3 regulates RNA polymerase II promoter-proximal pause …
2023年3月1日 · Our data show that H3K4me3 has a key role in regulating RNAPII pause-release; however, notably, we did not detect a role for H3K4me3 in regulating transcription initiation. …
SETD1B-mediated broad H3K4me3 controls proper temporal
2025年3月4日 · We identified thousands of spermatid-specific broad H3K4me3 domains regulated by the SETD1B-RFX2 axis, representing a previously underappreciated form of H3K4me3.
Nature:揭示H3K4me3在转录调控中的具体作用 - 知乎
在众多的组蛋白修饰中,基因活化状态的标志物组蛋白H3上第4位的赖氨酸三甲基化( H3K4me3 )是被研究得最为广泛的PTMs之一,在哺乳动物细胞中其可以被6种不同的 COMPASS复合 …
mRNA m6A regulates gene expression via H3K4me3 shift in 5’ …
2025年3月12日 · The observed shift in H3K4me3 is genetically controlled by m6A modifiers and influences gene expression. MTA, the m6A methylase, preferentially binds to phosphorylated …
Roles of H3K4 methylation in biology and disease - ScienceDirect
2025年2月1日 · In this review, we focus on recent studies that have yielded insights into how levels and patterns of H3K4me3 are regulated, how H3K4me3 contributes to the regulation of …