2024年12月25日 · GPR31 (G Protein-Coupled Receptor 31) is a Protein Coding gene. Diseases associated with GPR31 include Ischemia and Vulvar Dystrophy . Among its related pathways …

2019年1月23日 · Mice that lack GPR31, which was highly and selectively expressed in intestinal CX3CR1 + cells, showed defective dendrite protrusions of CX3CR1 + cells in the small intestine.

Title: The G protein-coupled receptor GPR31 promotes membrane association of KRAS. The data implicate 12-HETER1 in a critical new role in the regulation of prostate cancer progression and …

2020年12月3日 · GPR31 (G-protein–coupled receptor 31) regulates PAR (protease-activated receptor)-4–mediated platelet activation resulting in orchestrated control of Rap1 …

We cloned and identified GPR31, a plasma membrane orphan G protein-coupled receptor that displays high affinity for the human 12-lipoxygenase-derived product 12-(S)-hydroxy-5,8,10,14 …

2017年12月11日 · Here, using integrative 'omics' analysis, we identified an arachidonate 12-lipoxygenase (ALOX12)–12-hydroxyeicosatetraenoic acid (12-HETE)–G-protein-coupled …

Gene ID: 2853, updated on 8-Feb-2025. Enables G protein-coupled receptor activity and arachidonate binding activity. Involved in G protein-coupled receptor signaling pathway and …

2024年3月5日 · 12-HETER1/GPR31, a high-affinity 12 (S)-hydroxyeicosatetraenoic acid receptor, is significantly up-regulated in prostate cancer and plays a critical role in prostate cancer …

GPR31 is a G i-coupled receptor expressed in platelets, which signals through 12(S)-HETE to potentiate plate-let aggregation, calcium flux, and dense granule release through the PAR4 …

These findings demonstrate that lactate and pyruvate, which are produced in the intestinal lumen in a bacteria-dependent manner, contribute to enhanced immune responses by inducing …