GP1BA glycoprotein Ib platelet subunit alpha [ (human)]
Biological, clinical features and modelling of heterozygous variants of glycoprotein Ib platelet subunit alpha (GP1BA) and glycoprotein Ib platelet subunit beta (GP1BB) genes responsible …
GP1BA gene: MedlinePlus Genetics
Binding of the GPIb-IX-V complex to von Willebrand factor allows platelets to stick to the blood vessel wall at the site of the injury. These platelets form clots, plugging holes in the blood …
Inherited thrombocytopenia: when a low platelet count does not …
2004年1月15日 · Recently, the combination of in vitro megakaryocytopoiesis and plasma levels of TPO and glycocalicin (eg, soluble GP1b) has been shown to be an effective method for …
GP1BA Gene - GeneCards | GP1BA Protein | GP1BA Antibody
2024年12月25日 · GP1BA (Glycoprotein Ib Platelet Subunit Alpha) is a Protein Coding gene. Diseases associated with GP1BA include Von Willebrand Disease, Platelet-Type and Bernard …
GP1B | definition of GP1B by Medical dictionary
A gene on chromosome 17pter-p12 that encodes the alpha subunit of the Ib-V-IX system of platelet surface membrane glycoproteins, which comprise the von Willebrand factor (vWF) …
Platelet Glycoprotein-Ib (GPIb) May Serve as a Bridge between …
The GP1b-IX-mediated platelet activation occurs through various signaling pathways, including the mitogen-activated protein kinase pathways, the phosphatidylinositol 3-kinase (PI3-kinase) …
Comprehensive Description of Monoallelic GP1BA Variants …
2020年11月5日 · GP1BA encodes the glycoprotein (GP) 1bα subunit of the GP1b/IX/V complex, the platelet receptor for von Willebrand factor (VWF) and a mediator of outside-in signalling …
GPIbalpha shedding and platelet clearance - Renhao Li
2015年7月15日 · The objective of this proposed project is to define the role of ectodomain shedding of glycoprotein GP1b? in mediating platelet clearance by utilizing a novel monoclonal …
GLYCOPROTEIN Ib, PLATELET, ALPHA POLYPEPTIDE; GP1BA
2007年1月26日 · Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein that functions as a receptor for von Willebrand factor (VWF; 613160). The main portion of the …
Syk Activity Is Dispensable for Platelet GP1b-IX-V Signaling
2017年6月9日 · GP1b was shown to signal via the FcRγ-ITAM (Fc Receptor γ-Immunoreceptor tyrosine-based activation motif) pathway, activating spleen tyrosine kinase (Syk) and other …
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