2024年12月25日 · GDAP1 (Ganglioside Induced Differentiation Associated Protein 1) is a Protein Coding gene. Diseases associated with GDAP1 include Charcot-Marie-Tooth Disease, Type …

Ganglioside-induced differentiation-associated protein 1 is a type of protein that in humans is encoded by the GDAP1 gene. [5] [6] This gene encodes a member of the ganglioside-induced …

2022年6月3日 · Charcot-Marie-Tooth (CMT) disease 4A is an autosomal-recessive polyneuropathy caused by mutations of ganglioside-induced differentiation-associated protein …

2004年5月11日 · GDAP1-related hereditary motor and sensory neuropathy (GDAP1-HMSN) is a peripheral neuropathy (also known as a subtype of Charcot-Marie-Tooth disease) that typically …

2025年2月9日 · GDAP1 is broadly expressed in cancer cell lines of different tissue origin. There is a consensus YY1 binding site in the GDAP1 core promoter. GDAP1 mutations should be …

2016年11月14日 · GDAP1 expression induces fission of mitochondria and peroxisomes by a currently elusive mechanism, while disease causing mutations in GDAP1 impede the protein’s …

The GDAP1 gene encodes a protein expressed in the central and peripheral nervous system, particularly in Schwann cells. GDAP1 is an integral membrane protein of the outer …

Ganglioside-induced differentiation-associated protein (GDAP1) encodes a ganglioside-induced differentiation-associated protein originally isolated using a tetracycline-regulated expression …

gdap1是线粒体裂变因子之一，隐性遗传方式通过功能丧失机制降低线粒体裂变活性，导致线粒体的碎裂和管状线粒体的扩大；而显性遗传则干扰线粒体融合、增加活性氧簇的产生，造成线粒 …

2025年2月8日 · GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance. Niemann A, Wagner KM, Ruegg M, Suter UNiemann …