The discovery in 1953 of the double helix, the twisted-ladder structure of deoxyribonucleic acid (DNA), by James Watson and Francis Crick marked a milestone in the history of science and gave rise to modern molecular biology, which is largely concerned with understanding how genes control the chemical processes within cells.

Before the genetic code could be deciphered, before scientists could understand the process by which deoxyribonucleic acid (DNA) directed the synthesis of proteins, they had to resolve a final mystery: as Francis Crick and other researchers insisted, there must be a messenger to transmit genetic information from the cell nucleus to the ...

The name of British Nobel laureate Francis Crick (1916-2004) is inextricably tied to the discovery of the double helix of deoxyribonucleic acid (DNA) in 1953, considered the most significant advance in the understanding of biology since Darwin's theory of evolution.

Embryology and the Organization of DNA in Higher Organisms, 1966-1976; From Molecular Biology to Neurobiology, 1976-2004; Additional Resources; Glossary

In this article Crick explained how his theory regarding the flow of genetic information in the cell, which he had introduced in 1957 as the "Central dogma" of molecular biology, was well able to accommodate recent findings by Howard Temin and David Baltimore that certain oncogenic RNA viruses direct synthesis of DNA in virus-infected cells, a ...

In this paper Crick, Brenner, and their collaborators described a very elegant series of genetic experiments by which they proved that the genetic code for protein was a triplet code. They used an acridine dye, proflavin, to induce mutations in a specific, well-studied gene of a virus, a so-called bacteriophage, that attacked the bacterium ...

The Structure of DNA Creator: Watson, James D., 1928-Crick, Francis, 1916-2004 Date: 1953 Periodical: Cold Spring Harbor Symposia on Quantitative Biology Publisher: Cold Spring Harbor Laboratory. Press Rights: Reproduced with permission of Cold Spring Harbor Laboratory Press. Genre: Articles Format: Text Extent: 9 pages Language: English

A Structure for DNA (draft) Creator: Watson, James D., 1928-Crick, Francis, 1916-2004 Date: [1953] Description: A draft of Watson's and Crick's seminal article on the structure of Deoxyribonucleic acid, which appeared in the April 25, 1953, issue of Nature.

Crick, Francis, 1916-2004 Date: [ca. 1953] Genre: Drawings (visual works) 2. Letter from Francis Crick to James D. Watson

The name of British Nobel laureate Francis Crick (1916-2004) is inextricably tied to the discovery of the double helix of deoxyribonucleic acid (DNA) in 1953, considered the most significant advance in the understanding of biology since Darwin's theory of evolution.