2024年12月25日 · FUT1 (Fucosyltransferase 1 (H Blood Group)) is a Protein Coding gene. Diseases associated with FUT1 include Bombay Phenotype and Dowling-Degos Disease. Among its related pathways are superpathway of glycosphingolipids biosynthesis and Blood group systems biosynthesis.

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Galactoside 2-alpha-L-fucosyltransferase 1 is an enzyme that in humans is encoded by the FUT1 gene. [5] The enzyme is involved in the synthesis of the H antigen. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. ^ "Mouse PubMed Reference:".

The expression of FUT1, an alpha-1,2 fucosyltransferase, is remarkably down-regulated during melanoma progression, and the ectopic expression of FUT1 is sufficient to inhibit invadopodium formation and ECM degradation.

The four FUT1 alleles, h1 (547delAG), h2 (880delTT), h3 (C658T), and h4 (C35T; A980C) are most prevalent, which account for more than 90% of all allele counts and are essential to be involved when developing para-Bombay genotyping kit for Chinese.

2020年4月24日 · FUT1 and its fucosylated products are expressed in the ocular surface and ocular adnexa; however, the role of FUT1 in the ocular surface health and disease is yet unclear. Here, we investigated...

FUT1基因和FUT2基因编码的蛋白虽然都是α1，2-FUT，但因各自作用的底物不同，最终使得FUT1基因决定红细胞膜上H抗原的表达，FUT2基因决定H抗原物质在分泌腺和消化液中的表达 [1]。

岩藻糖基转移酶 1 (H 血型)： 该基因编码的高尔基体膜蛋白参与 H 抗原前体的产生，而 H 抗原是合成可溶性 A 和 B 抗原的最后一步所必需的。这是编码半乳糖苷 2-L-岩藻糖基转移酶的两个基因之一。该基因的突变是 H-Bombay 血型的原因。[RefSeq 提供，2016 年 8 月]

2025年2月8日 · Gene target information for FUT1 - fucosyltransferase 1 (H blood group) (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

2024年10月28日 · Clinical resource with information about FUT1, Bombay phenotype, Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease., Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo., Genetic variations affecting serum carcinoembryonic antigen levels and ...