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细胞外基质 (ECM)是由细胞分泌到细胞外间质中的大分子物质所构成的复杂网架动态结构，由间质基质和 基底膜 构成，占机体质量的三分之一以上。 间质基质主要由细胞分泌产生，是一种以Ⅰ型、Ⅲ型 胶原蛋白 、纤连蛋白、弹性蛋白和多种蛋白聚糖为主要成分的松散的胶原纤维网络结构。 基底膜是由IV型胶原蛋白、层粘连蛋白、巢蛋白以及 硫酸乙酰肝素蛋白聚糖 等构成的致密薄片状蛋白网络结构，它能够将细胞与周围的基质分开，作为物质运输的屏障发挥作用。 ECM组件 …

2024年12月24日 · ECM2 (Extracellular Matrix Protein 2) is a Protein Coding gene. Diseases associated with ECM2 include Fraser Syndrome 1 . Among its related pathways are Integrin Pathway and ERK Signaling .

ECM2 encodes extracellular matrix protein 2, so named because it shares extensive similarity with known extracelluar matrix proteins. Three transcript variants encoding different isoforms have been found for this gene.

2024年12月9日 · ECM2 encodes extracellular matrix protein 2, so named because it shares extensive similarity with known extracelluar matrix proteins. Three transcript variants encoding different isoforms have been found for this gene.

Extracellular matrix protein 2 is a protein that in humans is encoded by the ECM2 gene. [5] [6] ECM2 encodes extracellular matrix protein 2, so named because it shares extensive similarity with known extracellular matrix proteins. [6]

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This study identifies ECM2, for the first time, as a subtype marker and prognostic indicator for LGG. ECM2 could also provide a reliable guarantee for further personalized therapy, synergizing with tumor immunity, to break through the current limitations and thus reinvigorating immunotherapy for LGG.

ECM2 encodes extracellular matrix protein 2, so named because it shares extensive similarity with known extracelluar matrix proteins. Three transcript variants encoding different isoforms have been found for this gene.

Identification of a novel gene (ECM2) encoding a putative extracellular matrix protein expressed predominantly in adipose and female-specific tissues and its chromosomal localization to 9q22.3. ECM2编码细胞外基质蛋白2，因其与已知的细胞外基质蛋白具有广泛的相似性而得名。 已发现这个基因有三个编码不同异构体的转录变异体。 [由RefSeq，2010年10月提供]