DECR1 participates in the beta oxidation and metabolism of polyunsaturated fatty enoyl-CoA esters. Specifically, it catalyzes the reduction of 2,4 dienoyl-CoA thioesters of varying length …

2024年12月24日 · DECR1 (2,4-Dienoyl-CoA Reductase 1) is a Protein Coding gene. Diseases associated with DECR1 include 2,4-Dienoyl-Coa Reductase Deficiency and Hyperlysinemia. …

2,4-dienoyl-CoA reductase 1 is a protein that in humans is encoded by the DECR1 gene. [5] This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism …

2023年12月28日 · decr1是一种nadh依赖性的酸还原酶，它通过催化2,4-双烯酰辅酶a在β氧化过程中的还原反应来参与脂肪酸代谢。decr1的催化活性主要集中在线粒体内，作为脂肪酸β氧化途 …

Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis. 2,4-dienoyl-CoA reductase regulates lipid homeostasis in …

Our study delineates a molecular mechanism by which Decr1 potentiated higher mitochondrial lipid oxidation and cardiac damage by enhancing HADHA deacetylation through the …

2025年3月7日 · Decr1 (2,4-dienoyl-CoA reductase 1) was found to be significantly elevated in DCM mice across the four GEO databases, emphasizing its importance in DCM pathogenesis. …

decr1 是一种负调控雄激素受体 (ar) 靶基因，因此可能促进 pca 细胞存活和对 ar 靶向治疗的耐药性。decr1敲低选择性抑制pufa的β-氧化，抑制pca细胞（包括治疗耐药细胞系）的增殖和迁 …

2024年1月7日 · Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis.

关于 decr1 Cytogenetic location: 8q21.3 Genomic coordinates (GRCh38): 8:90,001,477-90,053,633 (from NCBI) This gene has 19 transcripts (splice variants), 212 orthologues and 1 …