DUSP6 - Wikipedia
Dual specificity phosphatase 6 (DUSP6) is an enzyme that in humans is encoded by the DUSP6 gene. [5] [6] [7]
DUSP6 Gene - GeneCards | DUS6 Protein | DUS6 Antibody
2024年12月24日 · DUSP6 (Dual Specificity Phosphatase 6) is a Protein Coding gene. Diseases associated with DUSP6 include Hypogonadotropic Hypogonadism 19 With Or Without …
《Nat Commun》解读：去磷酸化抑制泛素化！DUSP6调控Notch1 …
肿瘤中DUSP6高表达与较差的CRC患者总生存率相关，DUSP6表达升高与NTM水平升高相关。DUSP6过表达导致CRC细胞体外和体内增殖增强，DUSP6缺乏导致结直肠癌发展减少。在机 …
Nat Commun：揭示蛋白DUSP6促进结直肠癌生长机制
这项新的研究发现，DUSP6通过抑制一种通常会破坏一种名为Notch1的关键生长蛋白的过程来保护癌细胞，其中Notch1蛋白的作用类似于细胞通讯器，帮助 ...
Dual-specificity phosphatase 6 (DUSP6): a review of its molecular ...
Dual-specificity phosphatase 6 (DUSP6), a member of the MAPK phosphatase family, interacts with specifically targeted extracellular signal-regulated kinase 1/2 via negative feedback …
双特异性磷酸酶 6（DUSP6）基因 | MCE - MCE-生物活性分子 ...
DUSP6: VGNC: VGNC:61669: Compound Screening Libraries 实体化合物库 Virtual Screening 虚拟筛选 Customize Your Library 定制专属化合物库 Drug Screening Service 药物筛选服务 …
Dual-specificity phosphatase 6 (DUSP6): a review of its molecular ...
DUSP6 in breast cancer. DUSP6 expression was reported to play an oncogenic role in breast cancers 78,82,91. The specific role of the gene has been explored in triple-negative human …
双特异性蛋白磷酸酶6在肿瘤中作用的研究进展 - 冯 - 临床与病理杂志
双特异性蛋白磷酸酶6(dual specificity phosphatases 6，DUSP6)是一种双特异性蛋白磷酸酶，主要是负反馈调控反转录病毒相关的DNA序列-细胞外信号调节激酶1/2(retrovirus associated DNA …
DUSP6的上调通过负调节ERK通路并促进细胞凋亡来 ... - X-MOL
通过化学抑制剂或sirna抑制dusp6可以增加erk1 / 2的磷酸化，保护细胞免于凋亡，并促进ibv复制。dusp6的过表达降低了磷酸化-erk1 / 2的水平，促进了细胞凋亡，而显性负突变体dusp6-dn …
The MAPK dual specific phosphatase (DUSP) proteins: A versatile ...
2021年9月1日 · For instance, DUSP6 is highly expressed both in aged T cells and Tregs, and functions through deactivating ERK. In contrast, DUSP4 is responsible for aging T cell …