2021年4月7日 · Are you naturally a short sleeper? Mutations in the DEC2 gene decrease the need to sleep. Here's how to check your 23andMe / AncestryDNA data.

We have identified a mutation in a transcriptional repressor (hDEC2-P385R) that is associated with a human short sleep phenotype. Activity profiles and sleep recordings of transgenic mice …

Familial natural short sleep is a rare, genetic, typically inherited trait where an individual sleeps for fewer hours than average without suffering from daytime sleepiness or other consequences of …

2019年9月2日 · 近日，加州大学旧金山分校的Guangsen Shi、Louis Ptáček和傅嫈惠等 发现了迄今为止第二个短睡基因——突变的ADRB1。 携带这种基因突变的人，每天只需要睡4~6小时 …

2002年10月24日 · We found that Dec1 and Dec2, basic helix–loop–helix transcription factors, repressed Clock/Bmal1-induced transactivation of the mouse Per1 promoter through direct …

DEC2 is a transcription factor regulating the circadian clock in mammals, although its role in sleep regulation has been unclear. Here we report that prepro-orexin, also known as hypocretin …

经过大量研究，2009年，第一个短睡眠基因——DEC2被发现，也被称为撒切尔基因。 它能调节哺乳动物的睡眠长度，携带 DEC2基因 的特定突变的人，平均每晚只需要睡6.25小时，而缺乏这 …

《生物钟基因DEC2调控睡眠的机制》是依托华中科技大学，由张珞颖担任项目负责人的面上项目。 睡眠是一项基本的生命过程。 所有仔细研究过的动物，从蠕虫到人类，都具有睡眠或类似 …

2009年8月14日 · We have identified a mutation in a transcriptional repressor (hDEC2-P385R) that is associated with a human short sleep phenotype. Activity profiles and sleep recordings of …

2018年3月27日 · DEC2 is a transcription factor regulating the circadian clock in mammals, although its role in sleep regulation has been unclear. Here we report that prepro-orexin, also …