COPS5 Gene - GeneCards | CSN5 Protein | CSN5 Antibody
2024年12月24日 · COPS5 (COP9 Signalosome Subunit 5) is a Protein Coding gene. Diseases associated with COPS5 include Maxillary Sinus Adenocarcinoma and Xeroderma …
COP9 信号体亚基 5（COPS5）基因 | MCE - MCE-生物活性分子 ...
该基因编码的蛋白质是 COP9 信号体的八个亚基之一，COP9 信号体是一种高度保守的蛋白质复合物，在多个信号通路中起重要调节作用。 COP9 信号体的结构和功能类似于 26S 蛋白酶体的 …
COPS5 amplification and overexpression confers tamoxifen
2016年7月4日 · Overexpression of COPS5, through its isopeptidase activity, leads to ubiquitination and proteasome-mediated degradation of NCoR, a key corepressor for ERα and …
COP9 constitutive photomorphogenic homolog subunit 5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 or Csn5, is a gene conserved from humans to Saccharomyces cerevisiae. [5]
COPS5 COP9 signalosome subunit 5 [ (human)] - National Center …
2025年2月9日 · COPS5 is a novel RanBP9-binding protein that increases APP processing and Abeta generation by stabilizing RanBP9 protein levels
COPS5在肿瘤中作用的研究进展 - shjyyx.com
COPS5可通过抑制负调控蛋白和肿瘤抑制因子（P53、P27等）促进肿瘤发生,并与肿瘤进展及放化疗耐受性密切相关;针对COPS5的小分子抑制剂已被初步应用于临床。 在不久的将来,COPS5 …
Cops5 safeguards genomic stability of embryonic stem cells …
2020年2月4日 · Cops5 KO leads to decreased expression of the pluripotency marker Nanog, proliferation defect, G2/M cell-cycle arrest, and apoptosis of ESCs. Further analysis revealed …
COPS5在肿瘤中作用的研究进展 - 百度文库
COPS5是一种进化保守的多功能蛋白质，可以调节许多细胞进程，包括信号转导、细胞增殖、细胞凋亡、细胞周期控制、DNA损伤修复以及肿瘤发生 [2]。 我们对COPS5在肿瘤发生及发展中的 …
Jab1/COPS5 as a Novel Biomarker for Diagnosis, Prognosis, …
Jab1/COPS5 has spurred a strong research interest in developing inhibitors of oncogenes/oncoproteins for cancer therapy. In this paper, we present evidences …
COPS5 regulates osteosarcoma progression by upregulating …
2025年1月1日 · We found that COPS5 knockdown repressed proliferation, migration, and invasion and facilitated apoptosis of OS cells. Knockdown of COPS5 also restrained the tumor …