Circular RNAs (circRNAs) are a type of single-stranded RNAs that can form a covalently closed continuous loop acting as a microRNA (miRNA) sponge, interacts with RNA-binding proteins, or...

2016年1月16日 · CircNet is a database for circular RNAs. In version 2, 2732 samples from 37 types of cancers were integrated into CircNet 2.0 and analyzed using several of the most …

2022年1月7日 · In this article, we present our updates to CircNet (version 2.0), into which circRNAs from circAtlas and MiOncoCirc, and novel circRNAs from The Cancer Genome Atlas database have been integrated.

2021年11月26日 · The updated CircNet 2.0 aims to provide a more comprehensive resource of circRNA data derived from thousands of cancer samples and to allow the detection of novel circRNA from raw cancer data using reliable state-of-the-art algorithms.

Circnet 2.0 provides users with a series of methods to search for interested circRNAs with basic search, or search by BLAST, cancer type, CircBase ID and host gene. Mature miRNAs and gene symbols...

2016年9月2日 · The CircNet database is to our knowledge the first public database that provides tissue-specific circRNA expression profiles and circRNA-miRNA-gene regulatory networks.

2016年1月1日 · Circular RNAs (circRNAs) represent a new type of regulatory noncoding RNA that only recently has been identified and cataloged. Emerging evidence indicates that circRNAs exert a new layer of post-transcriptional regulation of gene expression.

2021年1月21日 · We performed extensive experimentation to highlight different regions of genome sequence that preserve the most important information for identifying circular RNAs. CircNet significantly outperforms state-of-the-art approaches with a considerable margin 10.29% in terms F 1 measure.

Circular RNAs (circRNAs) represent a new type of regulatory noncoding RNA that only recently has been identified and cataloged. Emerging evidence indicates that circRNAs exert a new layer of post-transcriptional regulation of gene expression.

The CircNet database is the first public database that provides tissue-specific circRNA expression profiles and circRNA-miRNA-gene regulatory networks. It not only extends the most up to date catalog of circRNAs but also provides a thorough expression analysis of both previously reported and novel circRNAs.