2006年8月9日 · Cdc28 is the catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK) (26, 3). Homologs include CDK1 in animals and cdc2 in S. pombe. Waves of CDK …

2025年2月8日 · Enables RNA polymerase II complex binding activity; cyclin-dependent protein serine/threonine kinase activity; and histone binding activity. Involved in several processes, …

2012年6月11日 · Cdc28 initiates the cell cycle by activating cell-cycle–specific transcription factors that switch on a transcriptional program during late G1 phase. Cdc28 also has a cell …

The cyclin-dependent protein kinase (CDK) encoded by CDC28 is the master regulator of cell division in the budding yeast Saccharomyces cerevisiae. By mechanisms that, for the most …

Cdc28 initiates the cell cycle by activating cell-cycle–specific transcription factors that switch on a transcriptional program during late G1 phase. Cdc28 also has a cell-cycle–independent, direct …

In the budding yeast Saccharomyces cerevisiae, a single Cdk, Cdc28 (which is equivalent to Cdk1 in other organisms), associates with multiple cyclins to regulate the cell cycle. By contrast,...

2012年6月26日 · The cyclin-dependent kinase Cdc28 is the master regulator of the cell cycle in Saccharomyces cerevisiae. Cdc28 initiates the cell cycle by activating cell-cycle-specific …

2025年1月16日 · Cdc28 is a protein kinase in yeast that plays a significant role in regulating the cell cycle and ensuring proper DNA replication. It controls various stages of the cell cycle, …

We show that Cdc28 and the S-phase cyclin Clb6 specifically phosphorylate Swi6 at serine 160 in vitro and also direct nuclear export of Swi6 in vivo. We propose that Clb6 not only facilitates …

1998年8月3日 · We have examined connections between nutrients, and the expression and activity of Cln3–Cdc28 kinase that regulates the G 1 –S boundary of the cell cycle in yeast, a …