CDC20 is a protein related to the beta subunit of heterotrimeric G proteins. Near its C-terminus it contains seven WD40 repeats, which are multiple short, structural motifs of around 40 amino …

2024年12月24日 · CDC20 (Cell Division Cycle 20) is a Protein Coding gene. Diseases associated with CDC20 include Oocyte/Zygote/Embryo Maturation Arrest 14 and Infertility. Among its …

2017年9月3日 · 摘要: 细胞分裂后期促进复合物（APC）具有调节细胞周期进展的作用，经细胞分裂周期蛋白20（Cdc20）或Cdc20同系物1（Cdh1）活化后形成两种不同的E3泛素连接酶复合 …

Cell-division cycle protein 20 homologue (Cdc20) has important functions in chromosome segregation and mitotic exit. Cdc20 is the target of the spindle assembly checkpoint (SAC) and …

2024年2月9日 · Cdc20 is a key subunit of the MCC 2, 3, which is produced at unattached kinetochores by the SAC signaling pathway. The MCC binds and inhibits the APC/C E3 ligase …

2022年4月30日 · More recently, novel CDC20 functions have been demonstrated or suggested, including the regulation of apoptosis and stemness properties and a correlation with immune …

2013年7月20日 · 摘要:cdc20是细胞周期相关蛋白之一.在细胞分裂周期中,cdc20 是纺锤体组装检查点的靶向物和有丝分 裂后期促进复合体的正调控因子,在引导细胞周期中某些蛋白质的

CDC20 appears to act as a regulatory protein interacting with several Other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear …

In this review, we will discuss the physiological role of Cdc20 and its downstream substrates in vitro and in the transgenic mouse model reminiscent of the pathogenesis of human cancers. …

2017年3月1日 · Cdc20 is the target of the spindle assembly checkpoint (SAC) and a key cofactor of the anaphase-promoting complex or cyclosome (APC/C) E3 ubiquitin ligase, thus regulating …