整联蛋白β-3（Integrin β3）或 CD61（Cluster of differentiation 61）是一种蛋白质 ，在人类基因组中由 ITGB3 基因编码。 [ 7 ] CD61 是一种在 血小板 上表达的 分化簇 。

Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. [5] CD61 is a cluster of differentiation found on thrombocytes. [6]

cd61. 整合素 β-3、itgb3、gp3a. 表达 cd41 的血小板、表达 cd51 的巨噬细胞、内皮细胞、成纤维细胞、巨核细胞、破骨细胞、肥大细胞和巨噬细胞。 介导细胞粘附至不同的基质蛋白。 cd62e. e-选择素、sele、elam1. 激活的内皮细胞。

CD分子 ，又称 分化簇 （Cluster of Differentiation）或分化群，也叫 白细胞分化抗原 ，是不同谱系的白细胞在正常分化成熟的不同阶段及活化过程中，出现或消失的细胞表面标记。 CD分子对于机体的免疫反应十分重要，广泛分布于B细胞、T细胞、树突状细胞和NK细胞等免疫细胞的表面。

β3 integrin (ITGB3), also known as CD61 or GP3A, is one of the most widely studied components in the integrin family. As an adhesion receptor on the cell surface, ITGB3 participates in reprogramming tumor metabolism, shaping the stromal and immune microenvironment, facilitating epithelial to mesenchymal transition (EMT) and endothelial to ...

CD61. CD61 recognizes platelet glycoprotein IIIa, which is localized to platelets and megakaryocytes and acute myeloid leukemias with megakaryocytic differentiation. This antigen can be destroyed by heat-induced epitope retrieval, so it is recommended to use enzyme digestion (Pronase) on formalin-fixed, paraffin-embedded material to enhance its ...

cd61抗原又称gpiiia，是一种105 kd的糖蛋白，存在于血小板、单核细胞、内皮细胞、平滑肌细胞、b细胞、巨噬细胞、肥大细胞和成纤维细胞上。cd61抗原在血小板聚集中起作用，同时也作为纤维蛋白原、纤维连接蛋白、血管性血友病因子和卵裂素的受体。

3.血小板无力症中CD61表达很少或几乎不表达。 Identify platelets, megakaryocytes and platelet thrombi Distinguish TTP (diffuse CD61+ platelet rich thrombi) from DIC (no / sparse thrombi, Cardiovasc Pathol 2005;14:150) Count platelets in thrombocytopenic patients …

CD61是一个105KDa膜糖蛋白，表达于血小板、巨核细胞、破骨细胞和血管内皮细胞上。CD61可以与整合素β3反应，整合素β3链接在糖蛋白lla（CD41）上，形成CD41/CD61复合物（GP llb/llla）来调节血小板的粘附和聚集。

2024年4月1日 · Here the authors show that CD61 colocalizes and functionally combines with CD103 in the T cell synaptic response to promote antitumor T cell responses.