CD16 expression enables antibody-mediated degranulation and thus allows T cell receptor-independent cytotoxicity. In patients with severe COVID-19, CD16-positive T cells may lead to …

CD16 is a low affinity IgG receptor found on various immune cells such as natural killer cells and T-cells. It plays a role in antibody-dependent cell-mediated cytotoxicity and is also expressed …

2016年9月27日 · We found that human CD16− expressing monocytes have a broad spectrum of ADCC capacities and can kill cancer cell lines, primary leukemic cells and hepatitis B virus …

CD16 (FcγRIIIa) is type I transmembrane receptor containing two extracellular Ig-like domains. CD16 function is a low affinity IgG receptor mediating antibody-dependent cellular cytotoxicity …

2013年5月2日 · Key Points. Activated NK cells loose CD16 (FcRγIII) and CD62L through a metalloprotease called ADAM17.Inhibition of ADAM17 enhances CD16 mediated NK cell f

2013年5月2日 · The Fc receptor CD16 is present on essentially all CD56(dim) peripheral blood natural killer (NK) cells. Upon recognition of antibody-coated cells it delivers a potent signal to …

Analysis of CD14 + CD16 + monocytes by scRNA-seq identifies nine clusters with one group of clusters exhibiting an increased migratory and inflammatory phenotype. Human CD14 + …

CD16, also known as FcγRIII, is crucial in both innate and adaptive immunity. There are two isoforms: CD16A on NK cells, macrophages, and neutrophils, and CD16B mainly on …

CD16 (FcRγIII) is the Fc receptor present on CD56 +dim NK cells that identifies the most mature cell population belonging to this lineage.

1998年9月1日 · FcγRIII (CD16) is a receptor for complexed IgG, and its presence has been used extensively for immunomagnetic separation of CD16 − eosinophilic from CD16 + neutrophilic …