2024年6月13日 · Involved in cell proliferation, migration, adhesion and angiogenesis with loss of CD138 expression leading to enhanced motility and invasion of neoplastic cells (Oncotarget 2015;6:28693)

2023年1月17日 · Encoded by MME gene ; 85-110 kDa cell membrane metalloendopeptidase at 3q25.1-q25.2 that inactivates bioactive peptides, including atrial natriuretic factor, bombesin, β amyloid, endothelin 1, enkephalins, gastrin and substance P and through the cytoplasmic domain, directly interacts with ezrin / radixin / moesin proteins, Lyn kinase and the phosphatase and tensin homolog (PTEN) protein (J ...

2024年3月19日 · CD Markers - CD15. Hodgkin lymphoma: Reed-Sternberg cells in classic and follicular Hodgkin lymphoma (Am J Clin Pathol 2002;117:29)

CD30 specific chimeric antigen receptor T (CAR T) cells (Blood Cancer J 2017;7:e603, J Clin Oncol 2020;38:3794, Sci Rep 2022;12:10488, Front Immunol 2022;13:858021) 3 generations of anti-CD30 CAR T cells Phase I / II studies in relapsed / refractory CHL Association with anti-PD1 regimen can improve the efficacy of CD30 CAR T therapy

2021年5月13日 · Differentiation (OMIM: 143030 [Accessed 13 May 2021]) Fertilization (oocyte CD9 is required for sperm egg fusion) Regulates paranodal junction formation (between neurons and glia) Required for microparticle release from coated platelets (Platelets 2009;20:361) Triggers platelet activation and aggregation

Mature plasmacytoid dendritic cell proliferations (Curr Hematol Malig Rep 2018;13:477) Systemic mastocytosis (Leukemia 2016;30:914) Hairy cell leukemia (Am J Clin Pathol 2011;136:625) Increased plasmacytoid dendritic cells in Kikuchi lymphadenitis and …

2022年6月13日 · A protein (38 kD), encoded by the SYP gene; is an integral membrane glycoprotein localized to presynaptic neurosecretory vesicles (Am J Hum Genet 1990;47:551)

2022年6月13日 · Bone / head and neck / soft tissue: adamantinoma-like Ewing family tumor (Am J Surg Pathol 2013;37:772, Am J Surg Pathol 2019;43:187, Head Neck Pathol 2022 Jan 13 [Epub ahead of print]) Breast: myoepithelial carcinoma, metaplastic carcinoma Gynecological: Choriocarcinoma (Malays J Pathol 2017;39:175)

2022年3月18日 · CD3 gamma, delta and epsilon defects cause autosomal recessive severe combined immunodeficiency (no T cells, although B cells and NK cells are normal) (Pediatr Allergy Immunol 2013;24:257, OMIM: 608971 - Severe Combined Immunodeficiency [Accessed 21 March 2022], Curr Opin Allergy Clin Immunol 2004;4:479)

2024年5月23日 · Stains & CD markers CD370-371. Author: Nat Pernick, M.D. Last author update: 13 November 2019. Last staff ...