2023年1月17日 · Cluster of differentiation 10 Also called common acute lymphoblastic leukemia antigen (CALLA), membrane metalloendopeptidase (MME), neutral endopeptidase, membrane associated (NEP), neutral endopeptidase 24.11, neprilysin, …

2021年9月20日 · Rituximab is a chimeric murine / human anti-CD20 antibody used to treat B cell lymphomas; treatment may cause selection of CD20 negative (but CD79a positive) tumor subclones (Am J Surg Pathol 2005;29:1399, Ann Hematol 2020;99:2141)

Immunostains, routine stains and CD markers at PathologyOutlines.com. Page views in 2025 to date (this page and chapter topics): 804,814

2025年1月30日 · CD5 is a pan-T cell marker belonging to the scavenger receptor cysteine rich (SRCR) superfamily of receptors (Eur J Immunol 2016;46:1490)

2022年6月9日 · Synovial sarcoma (~10%, usually cytoplasmic staining) Thymic carcinoma ( Appl Immunohistochem Mol Morphol 2005;13:205 ) 50% of solid pseudopapillary tumor ( Mod Pathol 2006;19:1157 )

2024年3月19日 · CD Markers - CD15. Hodgkin lymphoma: Reed-Sternberg cells in classic and follicular Hodgkin lymphoma (Am J Clin Pathol 2002;117:29)

Targetable biomarker (Oncologist 2022 Aug 10 [Epub ahead of print]) High expression by neoplastic cells Low expression by normal cells Extracellular localization CD30 antibody drug conjugate (ADC): brentuximab vedotin (BV) (Blood Cancer J 2017;7:e603, Oncologist 2022 Aug 10 [Epub ahead of print])

2024年6月13日 · Involved in cell proliferation, migration, adhesion and angiogenesis with loss of CD138 expression leading to enhanced motility and invasion of neoplastic cells (Oncotarget 2015;6:28693)

2022年3月18日 · CD3 gamma, delta and epsilon defects cause autosomal recessive severe combined immunodeficiency (no T cells, although B cells and NK cells are normal) (Pediatr Allergy Immunol 2013;24:257, OMIM: 608971 - Severe Combined Immunodeficiency [Accessed 21 March 2022], Curr Opin Allergy Clin Immunol 2004;4:479)

2020年1月30日 · Marrow involvement detected in 10 - 20% of cases; CD30 is helpful in identifying bone marrow involvement (Histopathology 2013;63:13, Hum Pathol 2008;39:1331) Central nervous system involvement is more commonly seen with bone marrow involvement and is a poor prognostic finding