2022年11月21日 · Also has diffuse CAIX but is positive for CD10 and negative or focal for CK7; Loss of chromosome 3p commonly seen Papillary renal cell carcinoma: Clear glycogenated cytoplasm is rare Foamy macrophages and psammoma bodies are common Also usually positive for CK7 but negative or only focal CAIX and often has apical CD10 expression

Epithelial markers: low molecular weight keratin (CAM 5.2), AE1-AE3 cytokeratin cocktail, CK7, CK20, CEA and EMA Alternative epithelial markers on sarcomatoid carcinoma include p63, MOC-31 and TTF1 (Mod Pathol 2005;18:1471) Melanocytic markers: S100 (also a mesenchymal marker), HMB45, MelanA / Mart1

Bladder: CK7 CK20 GATA3 p40 p63 PDL1 22C3 uroplakin II Kidney: AMACR CAIX CD10 CK7 c-kit / CD117 fumarate hydratase INI1 / SMARCB1 MelanA PAX8 RCC SDHB SMA TFE3 vimentin WT1 Penis: CK5/6 and CK5 HPV p40 p63 Prostate: AMACR androgen receptor (AR) CK5/6 and CK5 ERG NKX3.1 p63 prostein (P501S) PSA PSAP PSMA Testis: AFP CD30 CK7 c-kit / …

2022年9月20日 · D. INSM1+, chromogranin+, CK7- punctate, p40-, Ki67 high. The tumor shown is small cell carcinoma of the lung. Of the choices listed, INSM1+, chromogranin+, CK7- punctate, p40-, Ki67 high (answer D) is the most likely immunoprofile. …

2021年5月13日 · Simultaneous expression of biliary antigens (CK7, CK19, OV6) and hepatocyte antigens (HepPar1, albumin, alpha-1 antitrypsin, biliary glycoprotein 1 detected by canalicular staining with polyclonal anti-CEA and occasionally alpha fetoprotein) and other markers, such as NCAM1 / CD56

2024年12月10日 · This neoplasm commonly arises in the setting of cirrhosis. The image demonstrates hepatocellular carcinoma, of which ~80% of cases arise in cirrhosis. Answer A is incorrect because diffuse CK7 expression would be expected in cholangiocarcinoma rather than HCC. Answer B is incorrect because hepatitis B is a risk factor for developing HCC.

2020年12月15日 · CD117+ (20% of BCC CD117+), CD43+ (40%), CK7+, CEA+, EMA+ (in ductal structures) p63+, SMA+, calponin+ (myoepithelial cell population at periphery of tumor islands) Clear cell melanoma (balloon cell melanoma) versus clear cell BCC: Intraepidermal pagetoid spread, variable melanin pigment

2022年4月2日 · Comment: The patient's past history of triple negative breast cancer is noted. Immunostains performed on the biopsy block show that the tumor cells are positive for pancytokeratin, TRPS1 and CK7, while negative for CK20, HepPar1, ER, PR, HER2, GATA3, TTF1 and PAX8. The immunoprofile is consistent with metastatic carcinoma with breast primary.

2020年10月26日 · A biopsy of 1 of multiple liver lesions in a 64 year old woman reveals metastatic carcinoma of unknown primary. The lesion is found to be strongly and diffusely CK7 and PAX8 positive. Carcinomas from which of the following primary sites of origin are PAX8 negative, thus eliminating this body site from the differential diagnosis? Endometrium Lung

2021年6月25日 · Stains - OSCAR cytokeratin. This website is intended for pathologists and laboratory personnel but not for patients.