2024年12月24日 · CDH23 (Cadherin Related 23) is a Protein Coding gene. Diseases associated with CDH23 include Pituitary Adenoma 5, Multiple Types and Deafness, Autosomal Recessive …

Cadherin 23 interacts with other proteins in the cell membrane as part of a protein complex that is involved in cell attachment. Research suggests that the cadherin 23 protein complex helps to …

Our series of studies demonstrated that CDH23 variants cause a broad range of phenotypes of non-syndromic hearing loss (DFNB12); from congenital profound hearing loss to late-onset …

Cadherin-23 (CDH23) mediates homotypic and heterotypic cell-cell adhesions in cancer cells. However, the epigenetic regulation, the biological functions, the mechanisms and the …

HGNC Approved Gene Symbol: CDH23. Cytogenetic location: 10q22.1 Genomic coordinates (GRCh38) : 10:71,396,920-71,815,947 (from NCBI) The CDH23 gene encodes a member of …

Mutant alleles of CDH23, a gene that encodes a putative calcium-dependent cell-adhesion glycoprotein with multiple cadherin-like domains, are responsible for both recessive DFNB12 …

CDH23 is expressed in retina and cochlea, and encodes otocadherin —a protein containing an extracellular domain with multiple cadherin repeats, a transmembrane domain and a …

2024年2月8日 · Tip-link filaments in sensory hair cells of the inner ear are made of homodimers of cadherin-23 (CDH23) and protocadherin-15 (PCDH15), two proteins essential for hearing and …

Several dozen mutations in the CDH23 gene have been identified in people with nonsyndromic hearing loss, which is loss of hearing that is not associated with other signs and symptoms. …

Cadherin-23 (Cdh23), a long-chain non-classical cadherin, exhibits strong homophilic and heterophilic binding. The physiological relevance of strong heterophilic binding with …