2024年12月24日 · CDH13 (Cadherin 13) is a Protein Coding gene. Diseases associated with CDH13 include Vater/Vacterl Association and Atherosclerosis. Among its related pathways are Cell junction organization and ERK Signaling. Gene Ontology (GO) annotations related to this gene include calcium ion binding and cadherin binding.

T-cadherin, also known as cadherin 13, H-cadherin (heart), and CDH13, is a unique member of the cadherin protein family. Unlike typical cadherins that span across the cell membrane with distinct transmembrane and cytoplasmic domains, T-cadherin lacks these features and is instead anchored to the cell's plasma membrane through a GPI anchor.

2015年10月13日 · Cadherin-13 (CDH13), a unique glycosylphosphatidylinositol-anchored member of the cadherin family of cell adhesion molecules, has been identified as a risk gene for...

CDH13 regulates axonal outgrowth and synapse formation, substantiating its relevance for neurodevelopmental processes. Several studies support the influence of CDH13 on personality traits, behavior, and executive functions. However, evidence for functional effects of common gene variation in the CDH13 gene in humans is sparse.

2025年1月4日 · CDH13 is associated with working memory performance in attention deficit/hyperactivity disorder. Arias-Vásquez A, et al. Genes Brain Behav, 2011 Nov. PMID 21815997. What's a GeneRIF? Hsa_circ_0000119 promoted ovarian cancer development via enhancing the methylation of CDH13 by sponging miR-142-5p.

2021年5月10日 · Cadherin-13 (CDH13) has been associated with autism and attention-deficit/hyperactivity disorder. CDH13 localizes at inhibitory presynapses, specifically of parvalbumin (PV) and somatostatin...

Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks. A Common CDH13 Variant Is Associated with Low Agreeableness and Neural Responses to Working Memory Tasks in ADHD.

2015年10月13日 · Cadherin-13 (CDH13), a unique glycosylphosphatidylinositol-anchored member of the cadherin family of cell adhesion molecules, has been identified as a risk gene for attention-deficit/hyperactivity disorder (ADHD) and various comorbid neurodevelopmental and psychiatric conditions, including depression, substance abuse, autism spectrum disorder an...

The CDH13 (cadherin 13) is a protein-coding gene located on chromosome 16. CDH13, also known as T-cadherin, is a unique cadherin protein that lacks the typical transmembrane and cytoplasmic domains found in other cadherins. It's anchored …

CDH13 is an atypical member of the cadherin family and is closely related to the clinicopathological factors and prognosis of many types of cancer. However, the role of CDH13 in clear cell renal cell carcinoma (ccRCC) remains unknown.