E-selectin, also known as CD62 antigen-like family member E (CD62E), endothelial-leukocyte adhesion molecule 1 (ELAM-1), or leukocyte-endothelial cell adhesion molecule 2 (LECAM2), is a selectin cell adhesion molecule expressed only on endothelial cells activated by cytokines.

E-selectin (also known as ELAM1 [Endothelial Leukocyte Adhesion Molecule-1], CD62E, or LECAM-2), was first identified in the 1980s. It primarily regulates the adhesion and stable arrest of leukocytes to the endothelium in various disorders (1, 2).

2024年3月4日 · Therefore, we developed a CD62E- and ROS-responsive drug delivery system using E-selectin binding peptide, Thioketal, and silk fibroin (ETS) to achieve targeted delivery and controlled release of Clematis triterpenoid saponins (CS) against activated VEC, and thus promote cartilage regeneration.

Therefore, we developed a CD62E- and ROS-responsive drug delivery system using E-selectin binding peptide, Thioketal, and silk fibroin (ETS) to achieve targeted delivery and controlled release of Clematis triterpenoid saponins (CS) against activated VEC, …

Binding of host inflammatory cells to the endothelium is a critical contributor to the vascular damage characteristic of severe meningococcal disease and is regulated by endothelial cell adhesion molecules such as ICAM-1, VCAM-1 and CD62E.

2001年1月1日 · E-selectin, also known as CD62E and ELAM-1 (endothelial-leukocyte adhesion molecule-1), is a member of selectin family that plays a pivotal role in the first step of adhesion (rolling) of leukocytes to endothelial cells , which is followed by integrin-mediated leukocyte arrest and endothelial transmigration. The selectin family of proteins, E ...

选择素家族由三个成员组成，以其最初被鉴定的细胞类型命名：E-选择素（内皮细胞）、P-选择素（血小板）和L-选择素（淋巴细胞）。 他们的CD命名分别是：CD62E、CD62P、CD62L。 选择素由负责碳水化合物识别的N末端钙依赖性凝集素结构域（CRD）、表皮生长因子样（EGF）结构域、一系列共有重复序列（CR）结构域、 跨膜结构域 和短胞质尾组成（图1）。 选择素具有钙 …

2012年1月1日 · E-selectin, also known as CD62 antigen-like family member E (CD62E), endothelial-leukocyte adhesion molecule 1 (ELAM-1), or leukocyte-endothelial cell adhesion molecule 2 (LECAM2), is a cell adhesion receptor expressed on endothelial cells activated by …

2017年7月10日 · CD15s/CD62E interaction plays a key role in the homing process of circulating leukocytes. We investigated the heterophilic interaction of CD15s and CD62E in brain metastasis-related cancer cell adhesion.