在另外一些自身免疫性疾病中，如多发性硬化病 [22]、类风湿关节炎 [23]、银屑病 [24]、Wegner’s肉芽肿病 [25]和重症肌无力 [26]等，虽然CD4+CD25+Tregs细胞的数量正常，但其 …

Moreover, CD25 is an exclusive subunit that entirely binds IL-2, while CD132 binds the shared γc family cytokines (IL-4, IL-7, IL-9, IL-15 and IL-21), and the CD122 subunit binds also IL-15. …

Clinical background Elevated levels of soluble interleukin-2 receptor α-chain (IL-2Ra/CD25) are detected in the serum of patients with a broad spectrum of conditions associated with T- or B …

CD25 CD25, also known as the α-subunit of the IL-2 receptor, is involved in the regulation of T cell function. Similar to mice with impaired FOXP3, IL-2Rα deficient mice exhibit lethal …

来源：Nature Cancer 11月9日，最新发表在Nature Cancer杂志上的一项研究中，来自伦敦大学学院癌症研究所、罗氏制药研究与早期开发部的科学家们开发了一种能结合CD25蛋白不同部位 …

1982年人类LDA（白细胞分化抗原）国际研讨会将世界上各实验室所制备的、针对人LDA的 单克隆抗体 经过系统鉴定后，统一命名为分化群（cluster of differentiation,CD）。 [2] IL-2受体的α …

CD25靶点的研究主要集中在免疫调节和抗癌治疗。今天靶点科普给大家带来CD25的作用机制和临床研究进展，欢迎大家学习和互动交流。 CD25作用机制CD25是IL-2受体的α链，与IL-2结合 …

CD25, also known as Cluster of Differentiation 25, is an essential molecule involved in immune responses. It is the alpha chain of the high-affinity interleukin-2 receptor (IL2RA) and is also …

2021年10月26日 · Treg是机体免疫调节的重要组成部分，帮助机体实现免疫稳态，但肿瘤中Treg的大量存在却导致了促进肿瘤生长的免疫抑制环境。

CD25 deficiency or interleukin 2 receptor alpha deficiency is an immunodeficiency disorder associated with mutations in the interleukin 2 receptor alpha (CD25) (IL2RA) gene. The …