This article is a brief overview of basic and clinical research on CCR4 and its ligands, which has eventually led to the development of a humanized defucosylated anti-CCR4 antibody …

CCR4 is a chemokine receptor selectively expressed on normal T cell subsets such as type 2 helper T cells, skin-homing T cells and regulatory T cells, and on skin-associated T cell …

2024年12月24日 · CCR4 (C-C Motif Chemokine Receptor 4) is a Protein Coding gene. Diseases associated with CCR4 include Mycosis Fungoides and Peripheral T-Cell Lymphoma. Among …

2014年8月2日 · This article is a brief overview of basic and clinical research on CCR4 and its ligands, which has eventually led to the development of a humanized defucosylated anti-CCR4 …

2021年11月4日 · CCR4 is a chemokine receptor mainly expressed by T cells. It is the receptor for two CC chemokine ligands, CCL17 and CCL22. Originally, the expression of CCR4 was …

CCR4 is a chemokine receptor found on a specific type of cells in patients with HL, and it is being targeted for treatment using a defucosylated antibody. AI generated definition based on: …

Recent studies in budding yeast have identified novel roles for Ccr4-Not as a key regulator of core nutrient signaling pathways that control cell growth and proliferation, including signaling …

The chemokine receptor CCR4 is a seven trans-membrane G protein-coupled cell surface receptor molecule (alternatively designated CD194) with selective expression on cells of the …

Our proprietary drug discovery and development engine has identified the cell surface receptor CCR4 (C-C Motif Chemokine Receptor 4) as a drug target that potentially has broad …

Findings suggest that C-C motif chemokine receptor 4 (CCR4) may be a potential new diagnostic and prognostic marker in hepatocellular carcinoma (HCC), and targeting CCR4 may be a …