
CCL19: a novel prognostic chemokine modulates the tumor …
CCL19 modulates tumor immune microenvironment features and predicts prognosis in breast cancer patients. (A) We implemented with the CIBERSORT algorithms and identified …
CCL19 Gene - GeneCards | CCL19 Protein | CCL19 Antibody
2024年12月24日 · CCL19 (C-C Motif Chemokine Ligand 19) is a Protein Coding gene. Diseases associated with CCL19 include Allergic Contact Dermatitis and Polyradiculoneuropathy. …
CCL19: a novel prognostic chemokine modulates the tumor …
2023年11月8日 · Background: CCL19 is a chemokine involved in cancer research due to its important role in the tumor microenvironment (TME) and clinical relevance in cancers. This …
CCR7 and its ligands: balancing immunity and tolerance
Here, we focus on the cellular and molecular mechanisms that enable CCR7 and its two ligands, CCL19 and CCL21, to balance immunity and tolerance.
CCL19 and CCR7 Expression, Signaling Pathways, and Adjuvant Functions ...
Chemokine (C–C motif) ligand 19 (CCL19) is a critical regulator of the induction of T cell activation, immune tolerance, and inflammatory responses during continuous immune …
Does CCL19 act as a double-edged sword in cancer development?
2021年12月28日 · Through the induction of anti-tumor immune responses and inhibition of angiogenesis, CCL19 exerts tumor-suppressive functions. In contrast, CCL19 also acts as a …
CCL19-producing fibroblasts promote tertiary lymphoid structure ...
2024年8月12日 · We identify a fibroblast lineage secreting CCL19 that facilitates lymphocyte trafficking to TLSs. CCL19 treatment promotes TLS neogenesis and prevents tumor growth in …
CCL19 - an overview | ScienceDirect Topics
CCL19 is a chemokine ligand that binds to the CCR7 receptor, triggering a signaling cascade that leads to the migration of peripheral immune cells towards lymph nodes. AI generated definition …
CCL19 C-C motif chemokine ligand 19 [ (human)] - National …
CCL19 is an antimicrobial protein with bacteriocidal activity against E. coli. CCL19 (rather than CCL21) may contribute to the accumulation of dendritic cells and macrophages in the inflamed …
Role of CCL19/21 and its possible signaling through CXCR3 in ...
Normal thymus (a–d) and CCL19/21-deficient thymus (e–h).a In the normal mouse thymus metallophilic macrophages are strategically positioned in the cortico-medullary zone (cmz), …
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