Bovine herpesvirus-2 belongs to the family Herpesviridae (dsDNA) and is similar in structure to human herpes simplex virus. It causes bovine mammillitis and pseudo-lumpy skin disease. Bovine ulcerative mammillitis is often associated with cold weather. Commonly in early winter and in first lactation heifers.

We present the complete genome sequence of bovine alphaherpesvirus 2 (BoHV-2), a member of the family Herpesviridae, subfamily Alphaherpesvirinae, genus Simplexvirus. BoHV-2 is the causative agent of bovine ulcerative mammillitis (bovine herpes mammillitis) and …

2020年3月30日 · Bovine alphaherpesvirus type 2 (BoHV-2) belongs to family Herpesviridae, subfamily Alphaherpesviridae and can cause two distinct, well-defined conditions: a generalized benign skin infection that somewhat mimics lumpy skin disease (LSD), referred to as Pseudo-Lumpy Skin Disease (PSLD) and a localized ulcerative mammillitis, referred to as ...

Cause: bovine herpes virus 2 (BHV-2). Signs: ulceration of the mammary skin and associated areas. Diagnosis: clinical signs, virus isolation, serology. Treatment: symptomatic, possibly topical anti-viral agents. Prognosis: variable, very good to guarded depending on severity. BHV-2 is found worldwide.

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Das BHV-2 ist der Erreger der bovinen Mamillitis. Die Bovine Mamillitis ist eine zumeist akut verlaufende Erkrankung, die sich hauptsächlich durch ulzerative Veränderungen an den Euterzitzen laktierender oder frisch trockengestellter Kühe manifestiert.

2025年1月15日 · 数据显示，BHV-1400可以在 单次给药4h内迅速、强效、选择性降低IgA肾病患者的致病性半乳糖缺陷型IgA1（Gd-IgA1）抗体水平，同时将IgA等免疫球蛋白的水平保持在正常范围内 。

2025年1月15日 · BHV-1400 是其专有 MoDE™ 平台的第二代 TRAP™ 降解剂，该药物能够快速、深度且选择性地降低半乳糖缺乏型IgA1（Gd-IgA1）。 TRAP 分子开启了免疫调节治疗的新时代，有针对性地清除致病蛋白质，同时保留健康免疫系统的正常功能。

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