2024年12月24日 · BAZ2A (Bromodomain Adjacent To Zinc Finger Domain 2A) is a Protein Coding gene. Diseases associated with BAZ2A include Inflammatory Spondylopathy and …

2024年3月4日 · BAZ2A, an epigenetic regulatory factor that affects ribosomal RNA transcription, has been shown to be highly expressed in several cancers and promotes tumor cell migration. …

2014年12月8日 · Here we show that the gene encoding BAZ2A (TIP5), a factor previously implicated in epigenetic rRNA gene silencing, is overexpressed in prostate cancer and is …

2022年1月27日 · 研究人员在再生肝脏中采用了汇合CRISPR敲除和激活筛选，以评估165个染色质调节蛋白。这两种筛选方法都发现了imitation-SWI的染色质重塑成分Baz2a和Baz2b，其以前 …

2024年5月15日 · In differentiated cells, BAZ2A associates with the long non-coding pRNA and ribosomal RNA, but is role in embryonic cells is unknown. The authors show that BAZ2A …

有助于 RNA 聚合酶 I 核心启动子序列特异性 DNA 结合活性。 预测参与 DNA 甲基化；组蛋白去乙酰化；和大分子代谢过程的负调控。 预计在染色质组织和组蛋白修饰的上游或内部起作用。 …

Bromodomain adjacent to zinc finger domain protein 2A is a protein that in humans is encoded by the BAZ2A gene. [5] [6] [7]

2024年5月2日 · We identified a type of nuclear body with PS features composed of BAZ2A that associates with active chromatin. BAZ2A bodies depend on RNA transcription and BAZ2A non …

2025年2月9日 · BAZ2A is overexpressed in prostate cancer, maintains its cell growth, regulates protein-coding genes, and interacts with EZH2 to silence genes repressed in metastasis. Its …

BAZ2A regulates numerous protein-coding genes and directly interacts with EZH2 to maintain epigenetic silencing at genes repressed in metastasis. BAZ2A overexpression is tightly …