2024年12月24日 · BATF3 (Basic Leucine Zipper ATF-Like Transcription Factor 3) is a Protein Coding gene. Diseases associated with BATF3 include Hematologic Cancer and Dendritic Cell …

2020年9月28日 · By programing CD8+ T cell survival and memory, BATF3 is a promising molecule to optimize adoptive T cell therapy in patients. BATF3 is a member of the AP-1 …

Here we show that the transcription factor Batf3 acts as a fate-decision factor with respect to Tconv versus Tregs by restraining Treg differentiation. Batf3 was preferentially expressed in …

Batf3−/− memory cells had an impaired ability to mount a robust recall response but remained functional. These findings reveal a novel cell intrinsic role of Batf3 in regulating CD8 T cell …

Here we show that deletion of the transcription factor Batf3 ablated development of CD8α + dendritic cells, allowing us to examine their role in immunity in vivo. Dendritic cells from Batf3-/ …

2025年2月8日 · Basic Leucine Zipper ATF-Like Transcription Factor 3 (BATF3), an AP-1 family transcription factor, is a glucocorticoid receptor coregulator whose interaction with …

Mechanistically, BATF3 regulated T cell apoptosis and longevity via the proapoptotic factor BIM. By programing CD8 + T cell survival and memory, BATF3 is a promising molecule to optimize …

2025年1月28日 · Essential role for Batf3-dependent dendritic cells in regulating CD8 T-cell response during SARS-CoV-2 infection. Donor Batf3 inhibits murine lung allograft rejection …

2025年1月29日 · The functions of BATF, BATF2, and BATF3 in DCs are closely related, and the compensatory mechanisms between them ensure that the immune system maintains …

2020年9月28日 · Two studies reveal a role for the transcriptional regulator BATF3 as a T cell–intrinsic factor mediating effective memory responses. This finding opens future avenues …