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Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in …
2023年1月15日 · The human breast cancer resistance protein (BCRP, gene symbol ABCG2) is an ATP-binding cassette (ABC) efflux transporter. It was so named because it was initially cloned …
Baltimore City Recreation and Parks Sports
TEAM MANAGERS ONLY – once paid, click the “Roster” button to enter your team into the standings and begin forming your roster. Once entered, the system will send an automated …
Inhibitors of Human ABCG2: From Technical Background to Recent …
The ATP-binding cassette transporter G2 (ABCG2; also known as breast cancer resistance protein, BCRP) has been suggested to be involved in clinical multidrug resistance (MDR) in …
Role of Breast Cancer Resistance Protein (BCRP/ABCG2) in …
Since cloning of the ATP-binding cassette (ABC) family member breast cancer resistance protein (BCRP/ABCG2) and its characterization as a multidrug resistance efflux transporter in 1998, …
Breast Cancer Resistance Protein - an overview - ScienceDirect
Breast cancer resistance protein (BCRP) is a half-molecule ATP-binding cassette transporter that pumps out various anticancer agents such as 7-ethyl-10-hydroxycamptothecin, topotecan and …
Structure and function of the human breast cancer resistance protein ...
The human breast cancer resistance protein (BCRP/ABCG2) is the second member of the G subfamily of the large ATP-binding cassette (ABC) transporter superfamily. BCRP was initially …
ABC Transporters: The Breast Cancer Resistance Protein
2022年1月1日 · BCRP is a membrane-bound transporter that can bind substrate molecules and transfer them across that lipid bilayer. When positioned at a cell’s external membrane, BCRP …
Novel inhibitors of breast cancer resistance protein (BCRP, ABCG2 ...
2023年2月1日 · Breast cancer resistance protein (BCRP) is a clinically relevant ATP-binding cassette (ABC) transporter for drug disposition. Inhibition of BCRP increases the plasma …
Breast Cancer Resistance Protein: A Potential Therapeutic
Breast Cancer Resistance Protein (BCRP) is an efflux transporter responsible for causing multidrug resistance (MDR). It is known to expel many potent antineoplastic drugs, owing to its …